Bleeding Academic Research Consortium

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Bleeding Academic Research Consortium
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview[edit | edit source]

In order to harmonize and create a universal definition of bleeding, the Bleeding Academic Research Consortium (BARC) was convened. Dr. C Michael Gibson chaired the subcommittee drafting the definition of bleeding types 0, 1 and 2; Dr. Gabriel Stegg chaired the subcommittee drafting the definition of bleeding types 3a and 3b; Dr. Harvey White chaired the subcommittee drafting the definitions of coronary artery bypass grafting bleeding; and Dr. Deepak Bhatt chaired the subcommittee on fatal bleeding. The committee was chaired by Dr. Roxana Mehran and Dr. Sunil Rao.

BARC Definition (DO NOT EDIT)[edit | edit source]

Bleeding Academic Research Consortium (BARC) definition for Bleeding: [1]

Type 0:

Type 1:

  • Bleeding that is not actionable and does not cause the patient to seek unscheduled performance of studies, hospitalization, or treatment by a health-care professional; may include episodes leading to self-discontinuation of medical therapy by the patient without consulting a health-care professional.

Type 2:

  • Any overt, actionable sign of hemorrhage (e.g., more bleeding than would be expected for a clinical circumstance, including bleeding found by imaging alone) that does not fit the criteria for type 3, 4, or 5 but does meet at least one of the following criteria:
  • requiring nonsurgical, medical intervention by a health-care professional,
  • leading to hospitalization or increased level of care, or
  • prompting evaluation

Type 3:

Type 3a:
  • Overt bleeding plus hemoglobin drop of 3 to < 5 g/dL* (provided hemoglobin drop is related to bleed)
  • Any transfusion with overt bleeding
Type 3b:
Type 3c:
  • Intracranial hemorrhage (does not include microbleeds or hemorrhagic transformation, does include intraspinal),
  • Subcategories confirmed by autopsy or imaging or lumbar puncture,
  • Intraocular bleed compromising vision.

Type 4:

  • CABG-related bleeding,
  • Perioperative intracranial bleeding within 48 h,
  • Reoperation after closure of sternotomy for the purpose of controlling bleeding
  • Transfusion of ≥ 5 U whole blood or packed red blood cells within a 48-h period,
  • Chest tube output more than or equal to 2L within a 24-h period

Type 5:

  • Fatal bleeding
Type 5a:
  • Probable fatal bleeding; no autopsy or imaging confirmation but clinically suspicious
Type 5b:
  • Definite fatal bleeding; overt bleeding or autopsy or imaging confirmation

References[edit | edit source]

  1. Mehran R, Rao SV, Bhatt DL, Gibson CM, Caixeta A, Eikelboom J; et al. (2011). "Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium". Circulation. 123 (23): 2736–47. doi:10.1161/CIRCULATIONAHA.110.009449. PMID 21670242.

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