Chromosome 20 | |
---|---|
File:Human male karyotpe high resolution - Chromosome 20 cropped.png Human chromosome 20 pair after G-banding. One is from mother, one is from father. | |
File:Human male karyotpe high resolution - Chromosome 20.png Chromosome 20 pair in human male karyogram. | |
Features | |
Length (bp) | 64,444,167 bp (GRCh38)[1] |
No. of genes | 516 (CCDS)[2] |
Type | Autosome |
Centromere position | Metacentric[3] (28.1 Mbp[4]) |
Complete gene lists | |
CCDS | Gene list |
HGNC | Gene list |
UniProt | Gene list |
NCBI | Gene list |
External map viewers | |
Ensembl | Chromosome 20 |
Entrez | Chromosome 20 |
NCBI | Chromosome 20 |
UCSC | Chromosome 20 |
Full DNA sequences | |
RefSeq | NC_000020 (FASTA) |
GenBank | CM000682 (FASTA) |
Chromosome 20 is one of the 23 pairs of chromosomes in humans. Chromosome 20 spans around 63 million base pairs (the building material of DNA) and represents between 2 and 2.5 percent of the total DNA in cells. Chromosome 20 was fully sequenced in 2001 and was reported to contain over 59 million base pairs representing 99.4% of the euchromatic DNA.[5] Since then, due to sequencing improvements and fixes, the length of chromosome 20 has been updated to just over 63 million base pairs.[6]
The following are some of the gene count estimates of human chromosome 20. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[7]
Estimated by | Protein-coding genes | Non-coding RNA genes | Pseudogenes | Source | Release date |
---|---|---|---|---|---|
CCDS | 516 | — | — | [2] | 2016-09-08 |
HGNC | 519 | 191 | 297 | [8] | 2017-05-12 |
Ensembl | 540 | 594 | 247 | [9] | 2017-03-29 |
UniProt | 550 | — | — | [10] | 2018-02-28 |
NCBI | 555 | 487 | 333 | [11][12][13] | 2017-05-19 |
The following is a partial list of genes on human chromosome 20. For complete list, see the link in the infobox on the right.
The following diseases are some of those related to genes on chromosome 20:[14]
Chr. | Arm[20] | Band[21] | ISCN start[22] |
ISCN stop[22] |
Basepair start |
Basepair stop |
Stain[23] | Density |
---|---|---|---|---|---|---|---|---|
20 | p | 13 | 0 | 333 | 1 | 5,100,000 | gneg | |
20 | p | 12.3 | 333 | 513 | 5,100,001 | 9,200,000 | gpos | 75 |
20 | p | 12.2 | 513 | 624 | 9,200,001 | 12,000,000 | gneg | |
20 | p | 12.1 | 624 | 915 | 12,000,001 | 17,900,000 | gpos | 75 |
20 | p | 11.23 | 915 | 1164 | 17,900,001 | 21,300,000 | gneg | |
20 | p | 11.22 | 1164 | 1275 | 21,300,001 | 22,300,000 | gpos | 25 |
20 | p | 11.21 | 1275 | 1441 | 22,300,001 | 25,700,000 | gneg | |
20 | p | 11.1 | 1441 | 1608 | 25,700,001 | 28,100,000 | acen | |
20 | q | 11.1 | 1608 | 1774 | 28,100,001 | 30,400,000 | acen | |
20 | q | 11.21 | 1774 | 1927 | 30,400,001 | 33,500,000 | gneg | |
20 | q | 11.22 | 1927 | 2051 | 33,500,001 | 35,800,000 | gpos | 25 |
20 | q | 11.23 | 2051 | 2232 | 35,800,001 | 39,000,000 | gneg | |
20 | q | 12 | 2232 | 2439 | 39,000,001 | 43,100,000 | gpos | 75 |
20 | q | 13.11 | 2439 | 2578 | 43,100,001 | 43,500,000 | gneg | |
20 | q | 13.12 | 2578 | 2758 | 43,500,001 | 47,800,000 | gpos | 25 |
20 | q | 13.13 | 2758 | 3077 | 47,800,001 | 51,200,000 | gneg | |
20 | q | 13.2 | 3077 | 3299 | 51,200,001 | 56,400,000 | gpos | 75 |
20 | q | 13.31 | 3299 | 3382 | 56,400,001 | 57,800,000 | gneg | |
20 | q | 13.32 | 3382 | 3493 | 57,800,001 | 59,700,000 | gpos | 50 |
20 | q | 13.33 | 3493 | 3770 | 59,700,001 | 64,444,167 | gneg |
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