Chronic lymphocytic leukemia epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Rim Halaby, M.D. [3]; Haytham Allaham, M.D. [4]

Overview[edit | edit source]

The age-adjusted incidence of chronic lymphocytic leukemia is 4.7 per 100,000 individuals in the United States. Chronic lymphocytic leukemia is a disease of the elderly and is rarely encountered in individuals under the age of 40 years. Most patients who are newly diagnosed with chronic lymphocytic leukemia are over the age 50 years. Males are more commonly affected with chronic lymphocytic leukemia than females. The number of deaths from chronic lymphocytic leukemia is 1.3 per 100,000 individuals in the United States.

Epidemiology and Demographics[edit | edit source]

Prevalence[edit | edit source]

• The prevalence of chronic lymphocytic leukemia ranges from a low of 10 to 50 cases per 100,000 individuals, with an average prevalence of 30 per 100,000 individuals.

Incidence[edit | edit source]

• The incidence of chronic lymphocytic leukemia in developed countries is 4 per 100,000 individuals. It increases to more than 30 per 100,000 individuals at the age of 80 years.^[1]
• In 2011, the age-adjusted incidence of chronic lymphocytic leukemia was 4.82 per 100,000 individuals in the United States.^[2]

Age[edit | edit source]

• Thereafter, the incidence of chronic lymphocytic leukemia increases with age.^[3]
• Chronic lymphocytic leukemia is a disease of the elderly and is rarely encountered among individuals under the age of 40 years.
• Most patients who are newly diagnosed with chronic lymphocytic leukemia are over the age 50.
• While the overall age-adjusted incidence of chronic lymphocytic leukemia in the United States is 4.4 per 100,000, the age-adjusted incidence of chronic lymphocytic leukemia by age category is:^[2]

• 1.4 per 100,000 individuals among individuals younger than 65 years of age.
• 25.2 per 100,000 individuals among individuals older than 65 years of age.

Gender[edit | edit source]

• Males are more commonly affected with chronic lymphocytic leukemia than females. (1.7:1)
• In the United States, the age-adjusted incidence of chronic lymphocytic leukemia by gender on 2011 is:^[2][4]
  • 6.44 per 100,000 individuals among males.
  • 3.51 per 100,000 individuals among females.

Race[edit | edit source]

• Chronic lymphocytic leukemia usually affects individuals of the Caucasian race. African American individuals are slightly less likely to develop chronic lymphocytic leukemia.^[5]

Gallery[edit | edit source]

References[edit | edit source]