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Cryptococcosis laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.; Yazan Daaboul, M.D.
Overview
[edit | edit source]There are no specific laboratory findings associated with cryptococcal infection, but it can be diagnosed through culture, CSF microscopy, or by cryptococcal antigen (CrAg) detection.
Laboratory Findings
[edit | edit source]There are no specific laboratory findings associated with cryptococcal infection, but it can be diagnosed through:[1][2][3]
- Culture
- CSF microscopy
- Cryptococcal antigen (CrAg) detection
- In patients with HIV-related cryptococcal meningitis, 55% of blood cultures and 95% of CSF cultures are positive and visible colonies can be detected within 7 days.
- The opening pressure in the CSF may be elevated, with pressures ≥25 cm H2O in 60% to 80% of patients.
References
[edit | edit source]- ↑ Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. Available at http://aidsinfo.nih.gov/contentfiles/lvguidelines/adult_oi.pdf Accessed on December 31, 2015.
- ↑ Maziarz EK, Perfect JR (2016). "Cryptococcosis". Infect Dis Clin North Am. 30 (1): 179–206. doi:10.1016/j.idc.2015.10.006. PMID 26897067.
- ↑ El Fane M, Badaoui L, Ouladlahsen A, Sodqi M, Marih L, Chakib A; et al. (2015). "[Cryptococcosis during HIV infection]". J Mycol Med. 25 (4): 257–62. doi:10.1016/j.mycmed.2015.09.008. PMID 26515783.
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