Categories
  Encyclosphere.org ENCYCLOREADER
  supported by EncyclosphereKSF

DAMGO

From Wikidoc - Reading time: 1 min

Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview[edit | edit source]

DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin.[1]

Its structure is H-Tyr-D-Ala-Gly-N-MePhe-Gly-OH.

References[edit | edit source]

  1. Handa BK, Land AC, Lord JA, Morgan BA, Rance MJ, Smith CF. "Analogues of β-LPH61–64 possessing selective agonist activity at μ-opiate receptors." European Journal of Pharmacology. 1981 Apr 9;70(4):531-40. PMID 6263640. doi:10.1016/0014-2999(81)90364-2

Template:Opioids


Template:WikiDoc Sources


Licensed under CC BY-SA 3.0 | Source: https://www.wikidoc.org/index.php/DAMGO
9 views | Status: cached on September 20 2024 03:54:24
↧ Download this article as ZWI file
Encyclosphere.org EncycloReader is supported by the EncyclosphereKSF