Dehydroemetine adverse effects

Dehydroemetine
MEBADIN^® Prescribing Information
General Information
Clinical Information
Dosage and Administration
Precautions
Use in Pregnancy
Adverse Effects
Drug Interactions
Storage

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Adverse Effects[edit | edit source]

Local Reactions[edit | edit source]

The injections are painful. Abscess formation is common. A local eczematous rash may follow inadvertent subcutaneous injection. Generalized urticarial and purpuric rashes are rare.

Neuromuscular Effects[edit | edit source]

Weakness and muscular pain are common, particularly in the limbs and neck. Dyspnoea may also occur as a result of generalized weakness. These symptoms are dose-related and often precede evidence of cardiotoxicity.

Cardiac Effects[edit | edit source]

Hypotension, precordial pain, tachycardia and dysrhythmias are the most frequent signs of cardiac impairment. Electrocardiographic changes, particularly flattening and inversion of the T wave and prolongation of the Q-T interval, provide an early indication of toxicity.^[1]

References[edit | edit source]

↑ "WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Protozoa: Amoebiasis and giardiasis: Dehydroemetine".

[1] "WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition: Protozoa: Amoebiasis and giardiasis: Dehydroemetine".

[1]