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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vishal Devarkonda, M.B.B.S [2] Anahita Deylamsalehi, M.D. [3]
According to the American Diabetic Association, screening for diabetes mellitus type 1 is not recommended. Nevertheless, there are some data proposing favorable effects within screened patients .
Study
Less DKA
Lower HbA1c
Lower insulin dose
Shorter hospitalization period
BABYDIAB and Munich
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+
-
+
DiPiS
+
+
-
Not determined
TEDDY
+
+
+
Not determined
DAISY
+
+
+
+
DIPP
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+
Not determined
Not determined
*TEDDY (The Environmental Determinants of Diabetes in the Young) study reported higher c-peptide level at least within 12 months after diagnosis , which is related to better response to immunologic interventions .[5]
*DIPP (Finnish Type 1 diabetes Prediction and Prevention ) reported lower rate of weight loss among patients who were screened for diabetes mellitus type 1 [8]
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↑ Winkler C, Schober E, Ziegler AG, Holl RW (2012). "Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies" . Pediatr Diabetes . 13 (4): 308–13. doi :10.1111/j.1399-5448.2011.00829.x . PMID 22060727 .
↑ Elding Larsson H, Vehik K, Bell R, Dabelea D, Dolan L, Pihoker C; et al. (2011). "Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up" . Diabetes Care . 34 (11): 2347–52. doi :10.2337/dc11-1026 . PMC 3198296 . PMID 21972409 .
↑ Lundgren M, Sahlin Å, Svensson C, Carlsson A, Cedervall E, Jönsson B; et al. (2014). "Reduced morbidity at diagnosis and improved glycemic control in children previously enrolled in DiPiS follow-up" . Pediatr Diabetes . 15 (7): 494–501. doi :10.1111/pedi.12151 . PMC 4190091 . PMID 24823816 .
↑ 5.0 5.1 Steck AK, Larsson HE, Liu X, Veijola R, Toppari J, Hagopian WA; et al. (2017). "Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls" . Pediatr Diabetes . 18 (8): 794–802. doi :10.1111/pedi.12485 . PMC 5529265 . PMID 28127835 .
↑ Kupila A, Muona P, Simell T, Arvilommi P, Savolainen H, Hämäläinen AM; et al. (2001). "Feasibility of genetic and immunological prediction of type I diabetes in a population-based birth cohort" . Diabetologia . 44 (3): 290–7. doi :10.1007/s001250051616 . PMID 11317658 .
↑ Hekkala AM, Ilonen J, Toppari J, Knip M, Veijola R (2018). "Ketoacidosis at diagnosis of type 1 diabetes: Effect of prospective studies with newborn genetic screening and follow up of risk children" . Pediatr Diabetes . 19 (2): 314–319. doi :10.1111/pedi.12541 . PMID 28544185 .
↑ Narendran P (2019). "Screening for type 1 diabetes: are we nearly there yet?" . Diabetologia . 62 (1): 24–27. doi :10.1007/s00125-018-4774-0 . PMC 6290651 . PMID 30426167 .
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