Esophageal cancer staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview[edit | edit source]

According to the American Joint Committee on Cancer, there are 4 stages of esophageal cancer based on the tumor spread.

Staging[edit | edit source]

The American Joint Committee on Cancer has designated staging by TNM classification to define cancer of the esophagus and esophagogastric junction:^[1][2]

Primary Tumor (T)[edit | edit source]

• TX: Primary tumor cannot be assessed

• T0: No evidence of primary tumor

• Tis: High-grade dysplasia

• T1: Tumor invades lamina propria, muscularis mucosa, or submucosa

• T1a: Tumor invades lamina propria or muscularis mucosae

• T1b: Tumor invades submucosa

• T2: Tumor invades muscularis propria

• T3: Tumor invades adventitia

• T4: Tumor invades adjacent structures

• T4a: Resectable tumor invading pleura, pericardium, or diaphragm

• T4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc.

Regional Lymph Nodes (N)[edit | edit source]

• NX: Regional lymph nodes cannot be assessed

• N0: No regional lymph node metastasis

• N1: Metastases in 1–2 regional lymph nodes

• N2: Metastases in 3–6 regional lymph nodes

• N3: Metastases in ≥7 regional lymph nodes

Distant Metastasis (M)[edit | edit source]

• M0: No distant metastasis

• M1: Distant metastasis

American Joint Committee on Cancer stage groupings^[3][edit | edit source]

Squamous Cell Carcinoma[edit | edit source]

Adenocarcinoma[edit | edit source]

References[edit | edit source]

Template:WikiDoc Sources