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Esophagitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ajay Gade MD[2]]

Overview[edit | edit source]

Common risk factors in the development of esophagitis are immunosuppression, alcohol use, smoking, excessive vomiting, certain medications, and surgery or radiation to the chest.

Risk Factors[edit | edit source]

Eosinophilic Esophagitis[edit | edit source]

Common risk factors in the development of EoE include:[1][2][3][4][5][6]

  • Age- EoE has a bimodal age distribution common in both children and adults.
  • Sex- Males are more prone to EoE than the females.
  • Weather- Cold and dry climate trigger EoE.
  • Location- EoE is common in people with a history of European ancestry.
  • Season- Summer and fall, this is because people stay outdoors during this time and the higher levels of the pollen and the other allergens during these seasons.
  • Family history- EoE runs in the family and it is more common in people with a positive family history of the EoE.
  • History of allergies- EoE is very common in patient with a history of allergies such as asthma, industrial exposures, environmental allergies, chronic respiratory disease, food allergies and atopic dermatitis.

Reflux Esophagitis[edit | edit source]

Common risk factors in the development of reflux esophagitis include:

References[edit | edit source]

  1. "Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. - PubMed - NCBI".
  2. "www.ncbi.nlm.nih.gov" (PDF).
  3. "Genetics of Eosinophilic Esophagitis - FullText - Digestive Diseases 2014, Vol. 32, No. 1-2 - Karger Publishers".
  4. Furuta GT, Katzka DA (2015). "Eosinophilic Esophagitis". N. Engl. J. Med. 373 (17): 1640–8. doi:10.1056/NEJMra1502863. PMC 4905697. PMID 26488694.
  5. Kocsis D, Tulassay Z, Juhász M (2015). "[Dietary and pharmacological aspects of eosinophilic esophagitis]". Orv Hetil (in Hungarian). 156 (23): 927–32. doi:10.1556/650.2015.30164. PMID 26027600.
  6. Jarosz M, Taraszewska A (2014). "Risk factors for gastroesophageal reflux disease: the role of diet". Prz Gastroenterol. 9 (5): 297–301. doi:10.5114/pg.2014.46166. PMC 4223119. PMID 25396005.

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