Herpes zoster causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; L. Katie Morrison, MD; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Shingles can only arise in individuals who have been previously exposed to chickenpox (varicella zoster). After a person recovers from chickenpox, the virus stays in the body in a dormant (inactive) state. Herpes zoster is not caused by the same virus that causes genital herpes, a sexually transmitted disease.The disease arises from various events which depress the immune system, such as aging, severe emotional stress, severe illness, immunosuppression or long-term use of corticosteroids.^[1][2] The cellular and immunological events that lead to reactivation are poorly understood.^[3] There have been recorded cases of outbreaks occurring due to unmanaged stress or other stresses to the skin such as pinching, biting or scratching of more sensitive areas, such as nipples, ears, and underarms.

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