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Human papillomavirus classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]
Overview[edit | edit source]
Human papillomavirus may have different presentations depending on the anatomical region of involvement and the virus type. Mainly it is classified to cutaneous, anogenital and other mucosal surfaces.
Classification[edit | edit source]
Based on tissue involvement, human papillomavirus (HPV) is classified in to 3 main groups:
- Cutaneous
- Anogenital
- Other Mucosal surfaces
Currently, 210 different types of HPV have been discovered and the number keeps increasing.[1][2] Clinical manifestations depend on which HPV type involve which anatomic area.[3][4]
Cutaneous lesions[edit | edit source]
| Clinical presentation | Frequently found types | Less Frequently found types |
|---|---|---|
| Common wart | 1, 2, 4 | 4, 26, 27, 29, 41, 57, 63, 65, 77, 117, 125, 128, 129, 130, 131, 132, 133, 148, 149 |
| Plantar wart | 1, 2 | 26, 27, 29, 41, 57, 63, 65, 77, 117, 125, 128, 129, 130, 131, 132, 133, 148, 149 |
| Flat and intermediate warts | 3, 10 | 26, 27, 28, 38, 41, 49, 75, 76, 126 |
| Common warts of meat, poultry, and fish handlers | 2, 7 | 1, 3, 4, 10, 28 |
| Epidermodysplasia verruciformis | 3, 5, 8 | 9 , 12 , 14 , 15 , 17 , 19–25 , 36–38 , 47 , 49 , 50 |
Anogenital lesions[edit | edit source]
| Clinical presentation | Frequently found types | Less Frequently found types |
|---|---|---|
| Low grade intraepithelial neoplasia(squamous cell carcinoma) | 6, 11 | 16, 18, 31, 33, 35, 42, 43, 44, 45, 51, 52, 54, 61, 70, 72, 74 |
| High grade intraepithelial neoplasia(squamous cell carcinoma) | 16, 18 | 6, 11, 31, 33, 34, 35, 39, 42, 44, 45, 51, 52, 56, 58, 66, 67 |
| Condylomata acuminata | 6, 11 | 40, 42–44, 54, 61, 70, 72, 81 |
| Genital bowen's disease | 16 |
Other mucosal lesions[edit | edit source]
| Clinical presentation | Frequently found types | Less Frequently found types |
|---|---|---|
| Buschke–Löwenstein tumor | 6, 11 | |
| Recurrent respiratory papillomatosis | 6, 11 | 16, 18, 31, 33, 35, 39 |
| Conjunctival papillomas and carcinomas | 6, 11, 16 |
References[edit | edit source]
- ↑ "Reference clones at International HPV Reference Center".
- ↑ Bernard HU, Burk RD, Chen Z, van Doorslaer K, zur Hausen H, de Villiers EM (2010). "Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments". Virology. 401 (1): 70–9. doi:10.1016/j.virol.2010.02.002. PMC 3400342. PMID 20206957.
- ↑ Jenson AB, Kurman RJ, Lancaster WD (1985). "Detection of papillomavirus common antigens in lesions of skin and mucosa". Clin. Dermatol. 3 (4): 56–63. PMID 2463866.
- ↑ Bzhalava D, Eklund C, Dillner J (2015). "International standardization and classification of human papillomavirus types". Virology. 476: 341–4. doi:10.1016/j.virol.2014.12.028. PMID 25577151.
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