Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
In anatomy, a lobe is a clear anatomical division or extension[1][2] that can be determined without the use of a microscope (at the gross anatomy level.) This is in contrast to a lobule, which is a clear division only visible histologically. [3]
In practice, this division can be somewhat subjective. For example, it can be difficult to precisely distinguish between a interlobar duct and a interlobular duct.
Furthermore, the distinction is not universally accepted, and some sources simply consider a lobule to be a small lobe.[4]