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MEST (gene)

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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Mesoderm-specific transcript homolog protein is a protein that in humans is encoded by the MEST gene.[1][2]

This gene encodes a member of the [alpha]/[beta] hydrolase fold family and has isoform-specific imprinting. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Three transcript variants encoding two distinct isoforms have been identified for this gene. A pseudogene for this locus is located on chromosome 6.[2]

References[edit | edit source]

  1. Nishita Y, Yoshida I, Sado T, Takagi N (Feb 1997). "Genomic imprinting and chromosomal localization of the human MEST gene". Genomics. 36 (3): 539–42. doi:10.1006/geno.1996.0502. PMID 8884280.
  2. 2.0 2.1 "Entrez Gene: MEST mesoderm specific transcript homolog (mouse)".

Further reading[edit | edit source]




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