MYOC
From Wikidoc - Reading time: 3 min
| Myocilin, trabecular meshwork inducible glucocorticoid response | |||||||||||
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| Identifiers | |||||||||||
| Symbols | MYOC ; GLC1A; GPOA; JOAG; JOAG1; TIGR; myocilin | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 220 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE MYOC 210155 at tn.png | |||||||||||
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| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
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Ongoing Trials on MYOC at Clinical Trials.gov Clinical Trials on MYOC at Google
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US National Guidelines Clearinghouse on MYOC
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Directions to Hospitals Treating MYOC Risk calculators and risk factors for MYOC
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Myocilin, trabecular meshwork inducible glucocorticoid response, also known as MYOC, is a human gene.
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.[1]
References[edit | edit source]
Further reading[edit | edit source]
- Fingert JH, Stone EM, Sheffield VC, Alward WL (2003). "Myocilin glaucoma". Survey of ophthalmology. 47 (6): 547–61. PMID 12504739.
- Polansky JR (2004). "Current perspectives on the TIGR/MYOC gene (Myocilin) and glaucoma". Ophthalmology clinics of North America. 16 (4): 515–27, v–vi. PMID 14740993.
- Coca-Prados M, Escribano J (2007). "New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland". Progress in retinal and eye research. 26 (3): 239–62. doi:10.1016/j.preteyeres.2007.01.002. PMID 17321191.
 | This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it. |
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