Manchester score

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview[edit | edit source]

Manchester score is an indicator of prognosis in small cell lung cancer.^[1]^[2] It is calculated from a number of physical and biochemical markers.

A patient with small cell lung cancer scores one point for each of the following: -

Serum lactate dehydrogenase exceeds the upper limit of the reference range.
Serum sodium concentration less than 132 mmol/l.
Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
Serum bicarbonate less than 24.
Karnofsky performance status less than 60.
Extensive stage disease.

Prognosis[edit | edit source]

**Prognosis of small cell lung cancer according to Manchester score**^[3]
Manchester score	Prognostic group	Two year survival (%)
0-1	Good	16.2
2-3	Medium	2.5
4 or more	Poor	0

References[edit | edit source]

↑ Cerny, T (1987). "Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients". International Journal of Cancer. 39 (2): 146–149. Unknown parameter |coauthors= ignored (help)
↑ Kawahara, Masaaki (1996). "Prognostic factors and prognostic staging system for small cell lung cancer". Japanese Journal of Clinical Oncology. Oxford University Press. 27 (3): 158–165. ISSN: 0368-2811. Unknown parameter |coauthors= ignored (help)
↑ Maestu, I (Jun 1997). "Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients". Annals of Oncology. 8 (6): 547–553. Unknown parameter |coauthors= ignored (help)

Template:WikiDoc Sources

[Cerny-1] Cerny, T (1987). "Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients". International Journal of Cancer. 39 (2): 146–149. Unknown parameter |coauthors= ignored (help)

[Kawahara-2] Kawahara, Masaaki (1996). "Prognostic factors and prognostic staging system for small cell lung cancer". Japanese Journal of Clinical Oncology. Oxford University Press. 27 (3): 158–165. ISSN: 0368-2811. Unknown parameter |coauthors= ignored (help)

[Maestu-3] Maestu, I (Jun 1997). "Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients". Annals of Oncology. 8 (6): 547–553. Unknown parameter |coauthors= ignored (help)

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