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NEMF (gene)

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear export mediator factor (NEMF) is a protein that in humans is encoded by the NEMF gene.[1]

Function[edit | edit source]

This gene encodes a component of the ribosome quality control complex.[2] The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor suppressor.

References[edit | edit source]

  1. ↑ "Entrez Gene: Nuclear export mediator factor".
  2. ↑ Shao S, Brown A, Santhanam B, Hegde RS (February 2015). "Structure and assembly pathway of the ribosome quality control complex". Molecular Cell. 57 (3): 433–44. doi:10.1016/j.molcel.2014.12.015. PMID 25578875.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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