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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Abbreviations: ABG = Arterial blood gases, BUN = Blood urea nitrogen, CBC = Complete blood count, CT = Computed tomography, CRP = C - reactive protein, ECG = Electrocardiogram, ESR = Erythrocyte sedimentation rate, IVP = Intravenous pyelography, KFT = Kidney function test, GI = Gastrointestinal, GFR = Glomerular filtration rate, MRI = Magnetic resonance imaging, PT = Prothrombin time
| Etiology | Clinical manifestations | Paraclinical findings | Comments | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms and signs | Lab findings | Imaging | ||||||||||||||||||||
| Fatigue/
Lethargy |
Thirst | Dizziness/
Confusion |
Muscle weakness/
cramp |
Somatic/
visceral pain |
Vomiting | Diarrhea | Tachypnea | Edema | Blood indices | Renal Funtion test | Electrolytes | Urine analysis | ABG | Other | Ultrasound | X-ray | CT | MRI | Other | |||
| Prerenal causes | Cholera[1][2][2][3] | +/- | + | - | - | - | +/- | + | - | - | Leukocytosis, ↑HCT | ↑BUN, ↑Cr | ↓Na, ↑Ca, ↑Mg | Not applicable | ↑Lactate, ↓HCO3 | Stool PCR, Stool culture, Serotyping | Not applicable | Not applicable | Not applicable | Not applicable | - | - |
| Dehydration[4][5] | + | + | - | +/- | - | +/- | +/- | - | - | Not applicable | ↑BUN, ↑Cr | ↓Na, ↑K, ↓Cl | Ketones and glucose, ↑Urine specific gravity | ↑Lactate, ↓HCO3 | Hypoglycemia | Not applicable | Not applicable | Not applicable | Not applicable | - | - | |
| Diarrhea and/or vomiting[6][7] | +/- | +/- | - | - | - | + | + | - | - | Leukocytosis with predominant neutrophilia, ↑ ESR | Not applicable | Not applicable | Ketones, Organic acids, Porphobilinogen, Aminolevulinic acid | Not applicable | Stool anion gap, Stool pH < 5.5, Stool culture, Serotyping, Enzyme immunoassay (rotavirus or adenovirus), LFT, Amylase, Lipase | Normal | Not applicable | Not applicable | Not applicable | - | - | |
| Drugs/toxins[8][9] | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | +/- | Not applicable | ↑BUN, ↑Cr, ↑CK | ↑K, ↓Mg, ↓Ca, ↓P | Ingested drug, Glucose, Aminoacid, Phosphate, Ketone, Hyaline cast, RBC | ↑Lactate, Metabolic acidosis | Toxicology, Rapid immunoassay | Nephropathy | Radioopaque substances, Ingested drug packets | Not applicable | Not applicable | - | - | |
| Shock[10] | +/- | +/- | +/- | +/- | +/- | +/- | - | +/- | - | ↑HCT, ↑PT and aPTT, Eosinophilia, Leukocytosis | ↓GFR, ↑BUN, ↑Cr | Not applicable | Not applicable | ↑Lactate | LFT, ↑BNP, ↑Troponin, D-dimer, Fibrinogen | Pulmonary embolism, Pericardial effusion, Cardiac tamponade, Pneumothorax, Thoracic or abdominal aortic aneurysm in RUSH (Rapid Ultrasound for Shock and Hypotension) | Pneumonia, Pneumothorax, Pulmonary edema, Widened mediastinum, Free air under the diaphragm | Traumatic brain injury, Stroke, Spinal injury, Pneumonia, Pneumothorax, Ruptured aneurysm, Aortic dissection, Pulmonary embolism | Not applicable | - | - | |
| Toxic megacolon[11] | +/- | +/- | +/- | - | + | + | +/- | - | - | Leukocytosis, Anemia, ↑ESR and CRP | ↑BUN, ↑Cr | ↓Na | Not applicable | Not applicable | Loss of haustra, Hypoechoic and thick bowel walls, Dilated colon > 6cm, Dilatation of ileal loops | Dilated colon, Free intraperitoneal air | Bowel perforation, Abscess | Not applicable | Not applicable | Endoscopy and colonoscopy | - | |