Most common symptoms seen in pneumomediastinum are sudden onset of pain in the chest and subcutaneous emphysema. In most cases, pain follows the signs of causative or underlying pathology such as exacerbation of asthma. Spontaneous pneumomediastinum in most cases presents without any symptoms. Besides chest pain, other frequent symptoms are cough, dyspnea or pain in the neck. Most specific finding on physical exam is Hamman's sign, which is a mediastinal crunch or click present on auscultation over the cardiac apex and the left sternal border synchronous with the heartbeat.
The clinical presentation of pneumomediastinum depends on the causative or precipitating factor. Common symptoms of pneumomediastinum include:[4][5][6][7][8]
↑Agut A, Talavera J, Buendia A, Anson A, Santarelli G, Gomez S (2015). "IMAGING DIAGNOSIS-SPONTANEOUS PNEUMOMEDIASTINUM SECONDARY TO PRIMARY PULMONARY PATHOLOGY IN A DALMATIAN DOG". Vet Radiol Ultrasound. 56 (5): E54–7. doi:10.1111/vru.12223. PMID25388364.
↑Chiu CY, Wong KS, Yao TC, Huang JL (March 2005). "Asthmatic versus non-asthmatic spontaneous pneumomediastinum in children". Asian Pac. J. Allergy Immunol. 23 (1): 19–22. PMID15997870.
↑name="pmid18721592">Caceres M, Ali SZ, Braud R, Weiman D, Garrett HE (September 2008). "Spontaneous pneumomediastinum: a comparative study and review of the literature". Ann. Thorac. Surg. 86 (3): 962–6. doi:10.1016/j.athoracsur.2008.04.067. PMID18721592.
↑Nakagawa, Hideki, Yamauchi, Miwa, Kusuyama, Toshiyuki, Fukuda, Hiroyuki, & Ogawa, Kaoru. "Cervical emphysema secondary to pneumomediastinum as a complication of childbirth". Ear, Nose and Throat Journal. 82(12): 948–51. Vancouver style error: initials (help); Check date values in: |access-date= (help); |access-date= requires |url= (help)
↑Riccio, John C.; Abbott, Jean (1990). "A simple sore throat?: Retropharyngeal emphysema secondary to free-basing cocaine". The Journal of Emergency Medicine. 8 (6): 709–712. doi:10.1016/0736-4679(90)90283-2. ISSN0736-4679.
↑Abbas, Paulette I.; Akinkuotu, Adesola C.; Peterson, Michelle L.; Mazziotti, Mark V. (2015). "Spontaneous pneumomediastinum in the pediatric patient". The American Journal of Surgery. 210 (6): 1031–1036. doi:10.1016/j.amjsurg.2015.08.002. ISSN0002-9610.
↑Andrade Semedo, Flávia Helena Monteiro; Silva, Rosário Santos; Pereira, Sónia; Alfaiate, Teresa; Costa, Teresa; Fernandez, Pilar; Pereira, Amélia (2012). "Pneumomediastino espontâneo: relato de um caso". Revista da Associação Médica Brasileira. 58 (3): 355–357. doi:10.1590/S0104-42302012000300017. ISSN0104-4230.