Psoriasis other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview[edit | edit source]

Skin biopsy may be helpful in the diagnosis of psoriasis. Common findings include perivascular and dermal inflammatory cell infiltration, vascular dilation, and absent granular layer.

Other Diagnostic Studies[edit | edit source]

Skin Biopsy[edit | edit source]

Skin biopsy may be helpful in the diagnosis of psoriasis. On an hematoxylin and eosin (H&E) stain, the following findings may be observed:^[1]

• Perivascular and dermal inflammatory cell infiltration
• Vascular dilation
• Absent granular layer
• Elongation of dermal papillae
• Parakeratosis
• Spongiform pustules of Kogoj (pathognomic of psoriasis)
• Munro's micro abscesses (pathognomic of psoriasis)
• Edema of dermal papillae
• In psoriasis, skin biopsy of the affected area of skin shows that the epidermal/suprapapillary thickness ratio is increased
• Basal cell layer is expanded

References[edit | edit source]

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