From Wikidoc - Reading time: 2 min
| calcium channel, voltage-dependent, R type, alpha 1E subunit | |
|---|---|
| Identifiers | |
| Symbol | CACNA1E |
| Alt. symbols | CACNL1A6 |
| Entrez | 777 |
| HUGO | 1392 |
| OMIM | 601013 |
| RefSeq | NM_000721 |
| UniProt | Q15878 |
| Other data | |
| Locus | Chr. 1 q25-q31 |
The R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.
They are poorly understood, but like Q-type calcium channels, they appear to be present in cerebellar granule cells. They have a high threshold of activation and relatively slow kinetics.