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RORB

From Wikidoc - Reading time: 2 min


RAR-related orphan receptor B
File:PBB Protein RORB image.jpg
PDB rendering based on 1k4w.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols RORB ; NR1F2; ROR-BETA; RZRB; bA133M9.1
External IDs Template:OMIM5 Template:MGI HomoloGene38250
RNA expression pattern
File:206443 at
File:242385 at
File:32381 at
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

RAR-related orphan receptor B, also known as RORB, is a human gene.

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.[1]

References[edit | edit source]

  1. "Entrez Gene: RORB RAR-related orphan receptor B".

Further reading[edit | edit source]

Template:WikiDoc Sources


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