Rogaine (now branded as Regaine outside the U.S.) is the brand name for minoxidil, when used as a topical drug to treat male pattern baldness. The solution is applied to the scalp daily to stimulate hair growth and help prevent hair loss. It is available over-the-counter (OTC) in the U.S. in a 2% minoxidil solution and also as a 5% minoxidil solution (Rogaine Extra Strength for Men). While the 2% solution can be used by either gender, the 5% solution is recommended for use by men only.
Clinical studies of the effectiveness of topical minoxidil have shown both a slowing of hair loss and some regrowth of hair in some (but not all) patients. These studies also show that these measurable changes disappear fairly rapidly (within one to two years) after discontinuation of treatment.
In 2006 Rogaine Foam was released. Prior to the foam, Rogaine came only in liquid form. The foam is meant to allow for better and easier application with fewer side effects. It also allows the scalp to absorb the minoxidil more efficiently.[1]
As a drug to combat hair loss, the most common side effect is itchy scalp. In some cases Minoxidil may initially cause an increase in hair loss.
There have been cases of allergic reactions to minoxidil or the non-active ingredient propylene glycol which is found in some forms of the topical version, such as Rogaine. Large amounts of minoxidil can cause hypotension, and it has been found that using petroleum jelly or tretinoin on the scalp with minoxidil can cause too much of the drug absorption by the scalp, as can using the drug on sunburned scalps.
If a person uses minoxidil to stop hair loss for a length of time and then stops taking the drug, hair loss will occur again.
Other side effects include:
All the side effects in the above list except for acne may be an indicator that too much of the drug is being used.
It has also been found that the drug can be passed from a mother to a child via breast milk.
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