Systemic disorder

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Robert G. Badgett, M.D.[1]

Systemic disorder, "such as high blood pressure, or systemic diseases, such as the flu, affect the entire body."^[1]

Differential diagnosis[edit | edit source]

For the differential diagnosis of systemic disorders, the mnemonic VINDICATE^[2] or VITAMINSABCEDK^[3] may help prompt considerations.

VINDICATE[edit | edit source]

V	Vascular
I	Infectious
N	Neoplastic
D	Degenerative
I	Iatrogenic
C	Congenital
A	Autoimmune	Systemic vasculitis^[4]
T	Trauma
E	Environmental

VITAMINS[edit | edit source]

V	Vascular
I	Infectious / Inflammatory
T	Traumatic / Toxic
A	Autoimmune or allergy
M	Metabolic
I	Iatrogenic / Idiopathic
N	Neoplastic
S	Social

External links[edit | edit source]

References[edit | edit source]

↑ Systemic. MedlinePlus. Available at https://medlineplus.gov/ency/article/002294.htm. Accessed 12/14/2021
↑ Johnson SM, Shah LM (2019). "Imaging of Acute Low Back Pain". Radiol Clin North Am. 57 (2): 397–413. doi:10.1016/j.rcl.2018.10.001. PMID 30709477.
↑ Zabidi-Hussin ZA (2016). "Practical way of creating differential diagnoses through an expanded VITAMINSABCDEK mnemonic". Adv Med Educ Pract. 7: 247–8. doi:10.2147/AMEP.S106507. PMC 4853007. PMID 27217805.
↑ Anonymous (2025), Systemic vasculitis (English). Medical Subject Headings. U.S. National Library of Medicine.

[1] Systemic. MedlinePlus. Available at https://medlineplus.gov/ency/article/002294.htm. Accessed 12/14/2021

[pmid30709477-2] Johnson SM, Shah LM (2019). "Imaging of Acute Low Back Pain". Radiol Clin North Am. 57 (2): 397–413. doi:10.1016/j.rcl.2018.10.001. PMID 30709477.

[pmid27217805-3] Zabidi-Hussin ZA (2016). "Practical way of creating differential diagnoses through an expanded VITAMINSABCDEK mnemonic". Adv Med Educ Pract. 7: 247–8. doi:10.2147/AMEP.S106507. PMC 4853007. PMID 27217805.

[4] Anonymous (2025), Systemic vasculitis (English). Medical Subject Headings. U.S. National Library of Medicine.

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