From Wikidoc - Reading time: 6 min
| Vomiting Resident Survival Guide Microchapters |
|---|
| Overview |
| Causes |
| Diagnosis |
| Treatment |
| Dos |
| Don'ts |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rinky Agnes Botleroo, M.B.B.S.
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Vomiting or Emesis means forcible emptying of the contents of stomach in which the stomach has to overcome the pressures that are normally in place to keep food and secretions within the stomach.Nausea and vomiting are most common causes for patients to seek primary care treatment, so it is very important to identify and properly manage the underlying problems causing vomiting.Though the mechanisms causing of nausea and vomiting are not completely understood, it is thought that the activation of a medullary vomiting centre by either afferent input from the gastrointestinal tract due to presence of local irritants or stimulation of the central chemoreceptor trigger zone by circulating emetogenic substances may cause vomiting.Dopamine and serotonin are the main transmitters both in central nervous system and gastrointestinal tract related vomiting. The most common causes of vomiting are Gastroenteritis, Migraine, Gastro peresis,Post operative, radiation and chemotherapy related vomiting, tumor, increased intracranial pressure,Hepatitis, Cholecystitis,Labyrithitis, Alcohol abuse, pregnancy induced vomiting. The management of most cases of nausea and vomiting depends on a good history and a detailed complete physical examination. Most episodes of vomiting that lasts for less than 48 hours have an existing triggering factor such as infection, viral illness, or food poisoning and can be managed by removing the triggering factor and by supportive therapy. Chronic and unexplained nausea and vomiting can be a difficult to treat as the cause is often obscure and requires special investigation.
Life-threatening causes of vomiting include[1]:
Common causes include: [3]
Shown below is an algorithm summarizing the diagnosis of Vomiting[4][5][6]
| Patient comes with vomiting | |||||||||||||||||||||||||
| Take complete history | |||||||||||||||||||||||||
Ask the following questions about vomiting ❑ How long have you had nausea and vomiting? ❑ How much have you vomited? ❑ What is the colour of the vomitus? ❑ Have you had previous episodes like this or this is the first time? ❑ Is there any foul smell of the vomitus? ❑ Is there only food particle or any other mucous/substance present with the vomitus? ❑ Have you notice any blood streaks mixed with vomitus? | |||||||||||||||||||||||||
Ask the related questions ❑ Did your nausea and vomiting occur right after eating? ❑ Do you have a fever? ❑ Do you take any other medication? ❑ Have you recently eaten out? ❑ Have you eaten any canned product? ❑ Have you suffered from headache or photophobia along with this vomiting? ❑ Did you have any abdominal pain? | |||||||||||||||||||||||||
Do general physical examination: ❑Look for signs of dehydration[7][8] *Look for sunken eyes[8] *Dry mouth/tongue, thirst[8] *Dry skin *Dizziness and a lack of focus[8] *Orthostatic blood pressure drop,tachycardia[8] *Light-headedness *Dark urine or decreased urine output *Increased capillary refill time[7] *Poor skin turgor *Tiredness *Appetite ❑ Perform abdominal examination *Look for any abdominal tenderness *Presence of bowel sound | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Do the following invetigations ❑ Complete blood count ❑ Electrolytes ❑ Liver function test ❑ Pancreatic enzymes ❑ USG of the abdomen if complains of abdominal pain. ❑ Pregnancy test if applicable. ❑ Abdominal X-ray and abdominal CT scan if any symptoms of mechanical obstruction ❑ Esophagogastroduodenoscopy if mucosal diseases such as ulcer or mass are suspected. ❑ Scintigraphic measures of solid phase gastric emptying (such as 99mTc-sulfur colloid in egg) are commonly used to evaluate gastric motion function in suspected gastroparesis. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| If patient gives history of | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
History of ❑ Abdominal pain ❑ Passage of loose stool | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Gastroenteritis |
❑ Photophobia ❑ Triggered by smell, light or loud sound ❑ Unilateral headache usually, maybe bilateral which stays for 2-3 days. ❑ May have history of taking wine, chocolate. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Migraine | Tumor | Metabolic disorder | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Weight loss, loss of appetite | Pain related to food, radiates to the back | presence of jaundice, hepatomegaly | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Gastric carcinoma | Pancreatitis | Hepatitis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Shown below is the treatment of Vomiting. [9]
| Mechanism | Name | Dose | Side effects |
|---|---|---|---|
| 5-HT3 antagonists | 4–8 mg q4–8 hours 1–2 mg q24 hours 0.075–0.25 mg q24 hours |
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| Benzamides | 10–20 mg q6–8 hours 10 mg q8–24 hours |
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| Phenothiazines | 5–10 mg q6–8 hours 12.5 –25 mg q4–6 hours 10–25 mg q4–6 hours 4–8 mg q8–12 hours |
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| Cannabinoids | 2.5–10 mg q6–8 hours 1–2 mg q8–12 hours |
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| Anticholinergics | 0.3–0.6 mg q24 hours |
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| Antihistamines | 25–50 mg q24 hours 25–50 mg q6–8 hours 25–75 mg q8 hours 25–100 mg q6–8 hours |
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| Benzodiazepines | 0.5–2 mg 0.25–1 mg |
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| Corticosteroids | 4–8 mg q4–6 hours |
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| Butyrophenones | 0.625–1.25 mg q24hours |
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| NK-1 Receptor Antagonists | 80–125 mg q24 hours |
Below is the algorithm showing the treatment of vomiting :
| Patient comes with vomiting | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motion sickness with labirynthitis[10] | Migraine | Post-operative or chemotherapy related vomiting | Gatroenteritis | Gastroperesis | Pregnancy induced vomiting | ||||||||||||||||||||||||||||||||||||||||||||||||
| Antihistamines | Phenothiazines | Phenothiazines,Cannabinoids,Corticosteroids,Aprepitant | Antibiotics | Prokinetic medications | ❑ Doxylamine succinate/pyridoxine hydrochloride[11] ❑ Complementary and alternative therapies, such as ginger, acupressure, and vitamin B6[10] | ||||||||||||||||||||||||||||||||||||||||||||||||
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