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XPOT

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Exportin-T is a protein that in humans is encoded by the XPOT gene.[1][2][3]

This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.[3]

References[edit | edit source]

  1. Kutay U, Lipowsky G, Izaurralde E, Bischoff FR, Schwarzmaier P, Hartmann E, Gorlich D (Jul 1998). "Identification of a tRNA-specific nuclear export receptor". Mol Cell. 1 (3): 359–69. doi:10.1016/S1097-2765(00)80036-2. PMID 9660920.
  2. Arts GJ, Fornerod M, Mattaj IW (May 1998). "Identification of a nuclear export receptor for tRNA". Curr Biol. 8 (6): 305–14. doi:10.1016/S0960-9822(98)70130-7. PMID 9512417.
  3. 3.0 3.1 "Entrez Gene: XPOT exportin, tRNA (nuclear export receptor for tRNAs)".

Further reading[edit | edit source]



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