6 March – the Philosophical Transactions of the Royal Society of London begins publication, the first scientific journal in English and the oldest to be continuously published.
12 April – the first recorded victim of the Great Plague of London dies. Over the summer it is thought to have spread as far as Derby and on 6 September the first plague death takes place in the Derbyshire village of Eyam.
31 October – Parliament passes the Five Mile Act preventing non-conformist ministers from coming within five miles of incorporated towns or the place of their former livings.[1]
7 November – The London Gazette begins publication as The Oxford Gazette.