June 18 – American Revolutionary War: In response to Iroquois and Loyalist attacks, the U.S. launches the Sullivan Expedition with the aim of destroying enemy Iroquois settlements in what is now central New York.
November 2 – The North Carolina General Assembly carves a new county from Dobbs County, North Carolina and names it Wayne County in honor of United States General Anthony Wayne.
August 6 – Henry M. Ridgely, United States Senator from Delaware from 1827 till 1829. (died 1847)
September 18 – Joseph Story, Associate Justice of the U.S. Supreme Court from 1811 till 1845. (died 1845)
October – Henry W. Edwards, United States Senator from Connecticut from 1823 till 1838. (died 1847)
Date unknown – George Poindexter, Governor of Mississippi in 1819 and from 1820 till 1822 and United States Senator from Mississippi from 1830 till 1835. (died 1853)