March 3 – The Purefoods TJ Giants won the PBA Philippine Cup crown with a 4–0 series victory over Alaska Aces. The title-conquest was their 8th championship.
August 18 – The Alaska Aces won their 13th league championship with a 4–2 series victory over the defending PBA Fiesta Conference champions San Miguel Beermen.
February 13 – Nonito Donaire knocksout Manuel Vargas in the third round to defend his interim WBA world super flyweight title.
March 13 – Manny Pacquiao defeats Joshua Clottey, controlling the fight from start to finish and winning by unanimous decision. This was the first boxing match held at Cowboys Stadium in Arlington, Texas, drawing more than 41,000 people. This was Pacquiao's first defense of his newly awarded WBOwelterweight title.
May 13 – Manny Pacquiao is officially proclaimed congressman of the lone district of Sarangani.
June 28 – Manny Pacquiao takes his oath of office as a congressman before Supreme Court Associate Justice Antonio T. Carpio in the Provincial Capitol of Sarangani in Municipality of Alabel.
November 13 – Manny Pacquiao defeats Antonio Margarito for the WBC super welterweight title, making Pacquiao the first and so far only boxer to win world titles in eight different weight classes.
December 4 — Nonito Donaire won against Wladimir Sidorenko via knockout in the fourth round to win the vacant WBC Continental Americas bantamweight title.[2]
^Kabiling, Genalyn (December 5, 2010). "Donaire wins by TKO". Manila Bulletin. Retrieved December 6, 2010.
^Terrado, Jonas (December 6, 2010). "PH booters make history". Manila Bulletin. Archived from the original on December 11, 2010. Retrieved December 7, 2010.