4-(dimethylamino)phenylazoxybenzene reductase

In enzymology, a 4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction

4-(dimethylamino)phenylazobenzene + NADP⁺ ${\displaystyle \rightleftharpoons }$ 4-(dimethylamino)phenylazoxybenzene + NADPH + H⁺

Thus, the two substrates of this enzyme are 4-(dimethylamino)phenylazobenzene and NADP⁺, whereas its 3 products are 4-(dimethylamino)phenylazoxybenzene, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase. Other names in common use include N,N-dimethyl-p-aminoazobenzene oxide reductase, dimethylaminoazobenzene N-oxide reductase, NADPH-dependent DMAB N-oxide reductase, and NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.

• Lashmet Johnson PR, Ziegler DM (1986). "Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol". J. Biochem. Toxicol. 1 (1): 15–27. doi:10.1002/jbt.2570010104. PMID 3152268.