4-acetamidobutyrate deacetylase

In enzymology, a 4-acetamidobutyrate deacetylase (EC 3.5.1.63) is an enzyme that catalyzes the chemical reaction

4-acetamidobutanoate + H₂O ${\displaystyle \rightleftharpoons }$ acetate + 4-aminobutanoate

Thus, the two substrates of this enzyme are 4-acetamidobutanoate and H₂O, whereas its two products are acetate and 4-aminobutanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 4-acetamidobutanoate amidohydrolase. This enzyme participates in urea cycle and metabolism of amino groups and lysine degradation.

• Haywood GW, Large PJ (1986). "4-Acetamidobutyrate deacetylase in the yeast Candida boidinii grown on putrescine or spermidine as sole nitrogen source and its probable role in polyamine catabolism". J. Gen. Microbiol. 132: 7–14. doi:10.1099/00221287-132-1-7.