In 1800, the arrondissements of Avignon, Apt, Carpentras and Orange were established. The arrondissement of Orange was abolished in 1926. Cavaillon replaced Apt as subprefecture in 1926, which was reverted in 1933.[2]
The borders of the arrondissements of Vaucluse were modified in January 2017:[3]
one commune from the arrondissement of Apt to the arrondissement of Avignon
two communes from the arrondissement of Avignon to the arrondissement of Apt
21 communes from the arrondissement of Avignon to the arrondissement of Carpentras
two communes from the arrondissement of Carpentras to the arrondissement of Avignon