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Blood
Blood proteins
Coagulation system
Topic: Category
From
Wikipedia
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t
e
Coagulation cascade
Coagulation factors
Primary hemostasis
(platelet activation)
von Willebrand factor (vWF)
Platelet membrane glycoproteins
:
Glycoprotein Ib (GPIb)
(
GP1BA
GP1BB
Glycoprotein IX (GP9)
)
Glycoprotein IIb/IIIa
(
GPIIb
GPIIIa
)
Glycoprotein VI (GPVI)
Intrinsic pathway
(contact activation)
High-molecular-weight kininogen (HMWK)
Bradykinin
Prekallikrein
Kallikrein
Factor XII (Hageman factor)
Factor XI
Factor IX
Factor VIII
Extrinsic pathway
(tissue factor)
Factor III (tissue factor)
Factor VII
Common pathway
Factor X
Factor V
Prothrombin (factor II)
Thrombin (factor IIa)
Fibrinogen (factor I)
(
FGA
,
FGG
)
Fibrin (factor Ia)
Factor XIII
Anticoagulant factors
Antithrombin (inhibits FII, FIX, FX, FXI, FXII)
Protein C (inhibits FV, FVIII)
Protein S (cofactor for protein C)
Protein Z (inhibits FX)
Protein Z-related protease inhibitor (ZPI) (inhibits FX, FXI)
Tissue factor pathway inhibitor (TFPI) (inhibits FIII)
Fibrinolytic factors
Plasminogen
Plasmin
Tissue plasminogen activator (tPA)
Urokinase
Plasminogen activator inhibitor-1 (PAI-1)
Plasminogen activator inhibitor-2 (PAI-2)
α
2
-Antiplasmin
α
2
-Macroglobulin
Thrombin-activatable fibrinolysis inhibitor (TAFI)
Coagulation markers
Platelet activation
Platelet factor 4 (PF4)
β-Thromboglobulin (β-TG)
Thrombin generation
Prothrombin fragment 1+2 (F1+2)
Thrombin–antithrombin complex (TAT)
Activated protein C–protein C inhibitor (APC–PCI)
Fibrin generation
Fibrinopeptide A (FpA)
Fibrinopeptide B (FpB)
Fibrin monomers (FM)
Fibrinolysis
Plasmin-α
2
-antiplasmin complex (PAP)
D-Dimer (DD)
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