This category groups enzymes that use nicotinamide adenine dinucleotide (NAD+ and its reduced form, NADH) in redox reactions. See also Category:NADPH-dependent enzymes.
In general, the NAD is not stably associated with the enzyme, being a coenzyme; hence, we call such enzymes "NADH-dependent" enzymes, rather than simply "NADH enzymes". By contrast, more stably bound ligands such as heme or iron-sulfur clusters are cofactors; thus, one speaks of "heme enzymes" or "iron-sulfur proteins".