Coniferyl-alcohol dehydrogenase

In enzymology, a coniferyl-alcohol dehydrogenase (EC 1.1.1.194) is an enzyme that catalyzes the chemical reaction

coniferyl alcohol + NADP⁺ ${\displaystyle \rightleftharpoons }$ coniferyl aldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are coniferyl alcohol and NADP⁺, whereas its 3 products are coniferyl aldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is coniferyl-alcohol:NADP⁺ oxidoreductase. This enzyme is also called CAD.

• Mansell RL, Babbel GR, Zenk MH (1976). "Multiple forms and specificity of coniferyl alcohol dehydrogenase from cambial regions of higher plants". Phytochemistry. 15 (12): 1849–1853. doi:10.1016/S0031-9422(00)88829-9.
• Wyrambik D, Grisebach H (1975). "Purification and properties of isoenzymes of cinnamyl-alcohol dehydrogenase from soybean-cell-suspension cultures". Eur. J. Biochem. 59 (1): 9–15. doi:10.1111/j.1432-1033.1975.tb02418.x. PMID 1250.