Great American Interchange

The Great American Biotic Interchange (commonly abbreviated as GABI), also known as the Great American Interchange and the Great American Faunal Interchange, was an important late Cenozoic paleozoogeographic biotic interchange event in which land and freshwater fauna migrated from North America to South America via Central America and vice versa, as the volcanic Isthmus of Panama rose up from the sea floor, forming a land bridge between the previously separated continents. Although earlier dispersals had occurred, probably over water, the migration accelerated dramatically about 2.7 million years (Ma) ago during the Piacenzian age.^[1] It resulted in the joining of the Neotropic (roughly South American) and Nearctic (roughly North American) biogeographic realms definitively to form the Americas. The interchange is visible from observation of both biostratigraphy and nature (neontology). Its most dramatic effect is on the zoogeography of mammals, but it also gave an opportunity for reptiles, amphibians, arthropods, weak-flying or flightless birds, and even freshwater fish to migrate. Coastal and marine biota were affected in the opposite manner; the formation of the Central American Isthmus caused what has been termed the Great American Schism, with significant diversification and extinction occurring as a result of the isolation of the Caribbean from the Pacific.^[2]

The occurrence of the interchange was first discussed in 1876 by the "father of biogeography", Alfred Russel Wallace.^[3][4] Wallace had spent five years exploring and collecting specimens in the Amazon basin. Others who made significant contributions to understanding the event in the century that followed include Florentino Ameghino, W. D. Matthew, W. B. Scott, Bryan Patterson, George Gaylord Simpson and S. David Webb.^[5] The Pliocene timing of the formation of the connection between North and South America was discussed in 1910 by Henry Fairfield Osborn.^[6]

Analogous interchanges occurred earlier in the Cenozoic, when the formerly isolated land masses of India and Africa made contact with Eurasia about 56 and 30 Ma ago, respectively.^{[7][8][9][10][11][12][13][14][15][16][17][excessive citations]}

After the late Mesozoic breakup of Gondwana, South America spent most of the Cenozoic era as an island continent whose "splendid isolation" allowed its fauna to evolve into many forms found nowhere else on Earth, most of which are now extinct.^[18] Its endemic mammals initially consisted primarily of metatherians (marsupials and sparassodonts), xenarthrans, and a diverse group of native ungulates known as the Meridiungulata: notoungulates (the "southern ungulates"), litopterns, astrapotheres, pyrotheres and xenungulates.^{[n 1][n 2]} A few non-therian mammals – monotremes, gondwanatheres, dryolestids and possibly cimolodont multituberculates – were also present in the Paleocene; while none of these diversified significantly and most lineages did not survive long, forms like Necrolestes and Patagonia remained as recently as the Miocene.^[25]

Marsupials appear to have traveled via Gondwanan land connections from South America through Antarctica to Australia in the late Cretaceous or early Tertiary.^{[26][n 3]} One living South American marsupial, the monito del monte, has been shown to be more closely related to Australian marsupials than to other South American marsupials (Ameridelphia); however, it is the most basal australidelphian,^{[n 4]} meaning that this superorder arose in South America and then dispersed to Australia after the monito del monte split off.^[26] Monotrematum, a 61-Ma-old platypus-like monotreme fossil from Patagonia, may represent an Australian immigrant.^[27][28] Paleognath birds (ratites and South American tinamous) may have made a similar migration around the same time to Australia and New Zealand.^[29][30] Other taxa that may have dispersed by the same route (if not by flying or oceanic dispersal) are parrots, chelid turtles, and the extinct meiolaniid turtles.

Marsupials remaining in South America included didelphimorphs (opossums), paucituberculatans (shrew opossums) and microbiotheres (monitos del monte). Larger predatory relatives of these also existed, such as the borhyaenids and the saber-toothed Thylacosmilus; these were sparassodont metatherians, which are no longer considered to be true marsupials.^[31] As the large carnivorous metatherians declined, and before the arrival of most types of carnivorans, predatory opossums such as Thylophorops temporarily attained larger size (about 7 kg).

Metatherians and a few xenarthran armadillos, such as Macroeuphractus, were the only South American mammals to specialize as carnivores; their relative inefficiency created openings for nonmammalian predators to play more prominent roles than usual (similar to the situation in Australia). Sparassodonts and giant opossums shared the ecological niches for large predators with fearsome flightless "terror birds" (phorusrhacids), whose closest living relatives are the seriemas.^[32][33] North America also had large terrestrial predatory birds during the early Cenozoic (the related bathornithids), but they died out before the GABI in the Early Miocene, about 20 million years ago. Through the skies over late Miocene South America (6 Ma ago) soared one of the largest flying birds known, Argentavis, a teratorn that had a wing span of 6 m or more, and which may have subsisted in part on the leftovers of Thylacosmilus kills.^[34] Terrestrial sebecid (metasuchian) crocodyliforms with ziphodont teeth^{[n 5]} were also present at least through the middle Miocene^{[35][36][37][38]} and maybe to the Miocene-Pliocene boundary.^[39] Some of South America's aquatic crocodilians, such as Gryposuchus, Mourasuchus and Purussaurus, reached monstrous sizes, with lengths up to 12 m (comparable to the largest Mesozoic crocodyliforms). They shared their habitat with one of the largest turtles of all time, the 3.3 m (11 ft) Stupendemys.

Xenarthrans are a curious group of mammals that developed morphological adaptations for specialized diets very early in their history.^[40] In addition to those extant today (armadillos, anteaters, and tree sloths), a great diversity of larger types was present, including pampatheres, the ankylosaur-like glyptodonts, predatory euphractines, various ground sloths, some of which reached the size of elephants (e.g. Megatherium), and even semiaquatic to aquatic marine sloths.^[41][42]

The notoungulates and litopterns had many strange forms, such as Macrauchenia, a camel-like litoptern with a small proboscis. They also produced a number of familiar-looking body types that represent examples of parallel or convergent evolution: one-toed Thoatherium had legs like those of a horse, Pachyrukhos resembled a rabbit, Homalodotherium was a semibipedal, clawed browser like a chalicothere, and horned Trigodon looked like a rhinoceros. Both groups started evolving in the Lower Paleocene, possibly from condylarth stock, diversified, dwindled before the great interchange, and went extinct at the end of the Pleistocene. The pyrotheres and astrapotheres were also strange, but were less diverse and disappeared earlier, well before the interchange.

The North American fauna was a typical boreoeutherian one, supplemented with Afrotherian proboscids.

The invasions of South America started about 40 Ma ago (middle Eocene), when caviomorph rodents arrived in South America.^[43][44][45] Their subsequent vigorous diversification displaced some of South America's small marsupials and gave rise to – among others – capybaras, chinchillas, viscachas, and New World porcupines. The independent development of spines by New and Old World porcupines is another example of parallel evolution. This invasion most likely came from Africa.^[46][47] The crossing from West Africa to the northeast corner of Brazil was much shorter then, due to continental drift, and may have been aided by island hopping (e.g. via St. Paul's Rocks, if they were an inhabitable island at the time) and westward oceanic currents.^[48] Crossings of the ocean were accomplished when at least one fertilised female (more commonly a group of animals) accidentally floated over on driftwood or mangrove rafts. Hutias (Capromyidae) would subsequently colonize the West Indies as far as the Bahamas,^[49][50] reaching the Greater Antilles by the early Oligocene.^[51] Over time, some caviomorph rodents evolved into larger forms that competed with some of the native South American ungulates, which may have contributed to the gradual loss of diversity suffered by the latter after the early Oligocene.^[18] By the Pliocene, some caviomorphs (e.g., Josephoartigasia monesi) attained sizes on the order of 500 kg (1,100 lb) or larger.^[52]

Later (by 36 Ma ago),^[53] primates followed, again from Africa in a fashion similar to that of the rodents.^[43] Primates capable of migrating had to be small. Like caviomorph rodents, South American monkeys are believed to be a clade (i.e., monophyletic). However, although they would have had little effective competition, all extant New World monkeys appear to derive from a radiation that occurred long afterwards, in the Early Miocene about 18 Ma ago.^[43] Subsequent to this, monkeys apparently most closely related to titis island-hopped to Cuba, Hispaniola, and Jamaica. Additionally, a find of seven 21-Ma-old apparent cebid teeth in Panama suggests that South American monkeys had dispersed across the seaway separating Central and South America by that early date. However, all extant Central American monkeys are believed to be descended from much later migrants, and there is as yet no evidence that these early Central American cebids established an extensive or long-lasting population, perhaps due to a shortage of suitable rainforest habitat at the time.^[54][55]

Fossil evidence presented in 2020 indicates a second lineage of African monkeys also rafted to and at least briefly colonized South America. Ucayalipithecus remains dating from the Early Oligocene of Amazonian Peru are, by morphological analysis, deeply nested within the family Parapithecidae of the Afro-Arabian radiation of parapithecoid simians, with dental features markedly different from those of platyrrhines. The Old World members of this group are thought to have become extinct by the Late Oligocene. Qatrania wingi of lower Oligocene Fayum deposits is considered the closest known relative of Ucayalipithecus.^[56][57]

Remarkably, the descendants of those few bedraggled "waifs" that crawled ashore from their rafts of African flotsam in the Eocene now constitute more than twice as many of South America's species as the descendants of all the flightless mammals previously resident on the continent (372 caviomorph and monkey species versus 136 marsupial and xenarthran species).^{[n 6]}

Many of South America's bats may have arrived from Africa during roughly the same period, possibly with the aid of intervening islands, although by flying rather than floating. Noctilionoid bats ancestral to those in the neotropical families Furipteridae, Mormoopidae, Noctilionidae, Phyllostomidae, and Thyropteridae are thought to have reached South America from Africa in the Eocene,^[59] possibly via Antarctica.^[60] Similarly, free-tailed bats (Molossidae) may have reached South America from Africa in as many as five dispersals, starting in the Eocene.^[59] Emballonurids may have also reached South America from Africa about 30 Ma ago, based on molecular evidence.^[59][61] Vespertilionids may have arrived in five dispersals from North America and one from Africa.^[59] Natalids are thought to have arrived during the Pliocene from North America via the Caribbean.^[59]

Tortoises also arrived in South America in the Oligocene. They were long thought to have come from North America, but a recent comparative genetic analysis concludes that the South American genus Chelonoidis (formerly part of Geochelone) is actually most closely related to African hingeback tortoises.^{[n 7][62]} Tortoises are aided in oceanic dispersal by their ability to float with their heads up, and to survive up to six months without food or water.^[62] South American tortoises then went on to colonize the West Indies^[63] and Galápagos Islands (the Galápagos tortoise). A number of clades of American geckos seem to have rafted over from Africa during both the Paleogene and Neogene.^[64] Skinks of the related genera Mabuya and Trachylepis apparently dispersed across the Atlantic from Africa to South America and Fernando de Noronha, respectively, during the last 9 Ma.^[65] Surprisingly, South America's burrowing amphisbaenians^[66] and blind snakes^[67] also appear to have rafted from Africa, as does the hoatzin, a weak-flying bird of South American rainforests.^[68]

The earliest traditionally recognized mammalian arrival from North America was a procyonid that island-hopped from Central America before the Isthmus of Panama land bridge formed, around 7.3 Ma ago.^[69] This was South America's first eutherian carnivore. South American procyonids then diversified into forms now extinct (e.g. the "dog-coati" Cyonasua, which evolved into the bear-like Chapalmalania). However, all extant procyonid genera appear to have originated in North America.^[70] The first South American procyonids may have contributed to the extinction of sebecid crocodilians by eating their eggs, but this view has not been universally viewed as plausible.^{[n 8][38]} The procyonids were followed to South America by rafting or island-hopping hog-nosed skunks^[71] and sigmodontine rodents.^{[72][73][74][75]} The oryzomyine tribe of sigmodontine rodents went on to colonize the Lesser Antilles to Anguilla.

One group has proposed that a number of large Neartic herbivores actually reached South America as early as 9–10 Ma ago, in the late Miocene, via an early incomplete land bridge. These claims, based on fossils recovered from rivers in southwestern Peru, have been viewed with caution by other investigators, due to the lack of corroborating finds from other sites and the fact that almost all of the specimens in question have been collected as float in rivers without little to no stratigraphic control.^[76] These taxa are a gomphothere (Amahuacatherium),^[77][78] peccaries (Sylvochoerus and Waldochoerus),^[79] tapirs and Surameryx, a palaeomerycid (from a family probably ancestral to cervids).^[80] The identification of Amahuacatherium and the dating of its site is controversial; it is regarded by a number of investigators as a misinterpreted fossil of a different gomphothere, Notiomastodon, and biostratigraphy dates the site to the Pleistocene.^[81][82][83] The early date proposed for Surameryx has also been met with skepticism.^[84]

Megalonychid and mylodontid ground sloths island-hopped to North America by 9 Ma ago.^[72] A basal group of sloths^[85] had colonized the Antilles previously, by the early Miocene.^[86] In contrast, megatheriid and nothrotheriid ground sloths did not migrate north until the formation of the isthmus. Terror birds may have also island-hopped to North America as early as 5 Ma ago.^[87]

The Caribbean Islands were populated primarily by species from South America, due to the prevailing direction of oceanic currents, rather than to a competition between North and South American forms.^[49][50] Except in the case of Jamaica, oryzomyine rodents of North American origin were able to enter the region only after invading South America.

The formation of the Isthmus of Panama led to the last and most conspicuous wave, the Great American Biotic Interchange (GABI), starting around 2.7 Ma ago. This included the immigration into South America of North American ungulates (including camelids, tapirs, deer and horses), proboscids (gomphotheres), carnivorans (including felids such as cougars, jaguars and saber-toothed cats, canids, mustelids, procyonids and bears) and a number of types of rodents.^{[n 9]} The larger members of the reverse migration were ground sloths, terror birds, glyptodonts, pampatheres, capybaras, and the notoungulate Mixotoxodon (the only South American ungulate known to have invaded Central America).

In general, the initial net migration was symmetrical. Later on, however, the Neotropic species proved far less successful than the Nearctic. This difference in fortunes was manifested in several ways. Northwardly migrating animals often were not able to compete for resources as well as the North American species already occupying the same ecological niches; those that did become established were not able to diversify much, and in some cases did not survive for long.^[88] Southwardly migrating Nearctic species established themselves in larger numbers and diversified considerably more,^[88] and are thought to have caused the extinction of a large proportion of the South American fauna.^[71][89][90] (No extinctions in North America are plainly linked to South American immigrants.^{[n 10]}) Native South American ungulates did poorly, with only a handful of genera withstanding the northern onslaught. (Several of the largest forms, macraucheniids and toxodontids, have long been recognized to have survived to the end of the Pleistocene. Recent fossil finds indicate that one species of the horse-like proterotheriid litopterns did, as well.^[92] The notoungulate mesotheriids and hegetotheriids also managed to hold on at least part way through the Pleistocene.)^[A] South America's small marsupials, though, survived in large numbers, while the primitive-looking xenarthrans proved to be surprisingly competitive and became the most successful invaders of North America. The African immigrants, the caviomorph rodents and platyrrhine monkeys, were less impacted by the interchange than most of South America's 'old-timers', although the caviomorphs suffered a significant loss of diversity,^{[n 11][n 12]} including the elimination of the largest forms (e.g. the dinomyids). With the exception of the North American porcupine and several extinct porcupines and capybaras, however, they did not migrate past Central America.^{[n 13]}

Due in large part to the continued success of the xenarthrans, one area of South American ecospace the Nearctic invaders were unable to dominate was the niches for megaherbivores.^[94] Before 12,000 years ago, South America was home to about 25 species of herbivores weighing more than 1,000 kg (2,200 lb), consisting of Neotropic ground sloths, glyptodonts, and toxodontids, as well as gomphotheres and camelids of Nearctic origin.^{[n 14]} Native South American forms made up about 75% of these species. However, none of these megaherbivores has survived.

Armadillos, opossums and porcupines are present in North America today because of the Great American Interchange. Opossums and porcupines were among the most successful northward migrants, reaching as far as Canada and Alaska, respectively. Most major groups of xenarthrans were present in North America until the end-Pleistocene Quaternary extinction event (as a result of at least eight successful invasions of temperate North America, and at least six more invasions of Central America only). Among the megafauna, ground sloths were notably successful emigrants; four different lineages invaded North America. A megalonychid representative, Megalonyx, spread as far north as the Yukon^[96] and Alaska,^[97] and might well have invaded Eurasia had a suitable habitat corridor across Beringia been present.

Generally speaking, however, the dispersal and subsequent explosive adaptive radiation of sigmodontine rodents throughout South America (leading to over 80 currently recognized genera) was vastly more successful (both spatially and by number of species) than any northward migration of South American mammals. Other examples of North American mammal groups that diversified conspicuously in South America include canids and cervids, both of which currently have three or four genera in North America, two or three in Central America, and six in South America.^{[n 15][n 16]} Although members of Canis (specifically, coyotes) currently range only as far south as Panama,^{[n 17]} South America still has more extant genera of canids than any other continent.^{[n 15]}

The effect of formation of the isthmus on the marine biota of the area was the inverse of its effect on terrestrial organisms, a development that has been termed the "Great American Schism". The connection between the east Pacific Ocean and the Caribbean (the Central American Seaway) was severed, setting now-separated populations on divergent evolutionary paths.^[2] Caribbean species also had to adapt to an environment of lower productivity after the inflow of nutrient-rich water of deep Pacific origin was blocked.^[101] The Pacific coast of South America cooled as the input of warm water from the Caribbean was cut off. This trend is thought to have caused the extinction of the marine sloths of the area.^[102]

During the last 7 Ma, South America's terrestrial predator guild has changed from one composed almost entirely of nonplacental mammals (metatherians), birds, and reptiles to one dominated by immigrant placental carnivorans (with a few small marsupial and avian predators like didelphine opossums and seriemas). It was originally thought that the native South American predator guild, including sparassodonts, carnivorous opossums like Thylophorops and Hyperdidelphys, armadillos such as Macroeuphractus, terror birds, and teratorns, as well as early-arriving immigrant Cyonasua-group procyonids, were driven to extinction during the GABI by competitive exclusion from immigrating placental carnivorans, and that this turnover was abrupt.^[103][104] However, the turnover of South America's predator guild was more complex, with competition only playing a limited role.

In the case of sparassodonts and carnivorans, which has been the most heavily studied, little evidence shows that sparassodonts even encountered their hypothesized placental competitors.^{[105][106][107]} Many supposed Pliocene records of South American carnivorans have turned out to be misidentified or misdated.^[108][105] Sparassodonts appear to have been declining in diversity since the middle Miocene, with many of the niches once occupied by small sparassodonts being increasingly occupied by carnivorous opossums,^{[109][110][111][112][113]} which reached sizes of up to roughly 8 kg (~17 lbs).^[110] Whether sparassodonts competed with carnivorous opossums or whether opossums began occupying sparassodont niches through passive replacement is still debated.^{[113][112][111][110]} Borhyaenids last occur in the late Miocene, about 4 Ma before the first appearance of canids or felids in South America.^[106] Thylacosmilids last occur about 3 Ma ago and appear to be rarer at pre-GABI Pliocene sites than Miocene ones.^[105]

In general, sparassodonts appear to have been mostly or entirely extinct by the time most nonprocyonid carnivorans arrived, with little overlap between the groups. Purported ecological counterparts between pairs of analogous groups (thylacosmilids and saber-toothed cats, borhyaenids and felids, hathliacynids and weasels) neither overlap in time nor abruptly replace one another in the fossil record.^[103][106] Procyonids dispersed to South America by at least 7 Ma ago, and had achieved a modest endemic radiation by the time other carnivorans arrived (Cyonasua-group procyonids). However, procyonids do not appear to have competed with sparassodonts, the procyonids being large omnivores and sparassodonts being primarily hypercarnivorous.^[114] Other groups of carnivorans did not arrive in South America until much later. Dogs and weasels appear in South America about 2.9 Ma ago, but do not become abundant or diverse until the early Pleistocene.^[105] Bears, cats, and skunks do not appear in South America until the early Pleistocene (about 1 Ma ago or slightly earlier).^[105] Otters and other groups of procyonids (i.e., coatis, raccoons) have been suggested to have dispersed to South America in the Miocene based on genetic data, but no remains of these animals have been found even at heavily sampled northern South American fossil sites such as La Venta (Colombia), which is only 600 km (370 mi) from the Isthmus of Panama.^{[115][114][116][117]}

Other groups of native South American predators have not been studied in as much depth. Terror birds have often been suggested to have been driven to extinction by placental carnivorans, though this hypothesis has not been investigated in detail.^[118][119] Titanis dispersed from South America to North America against the main wave of carnivoran migrations, being the only large native South American carnivore to accomplish this.^[119] However, it only managed to colonize a small part of North America for a limited time, failing to diversify and going extinct in the early Pleistocene (1.8 Ma ago); the modest scale of its success has been suggested to be due to competition with placental carnivorans.^[120] Terror birds also decline in diversity after about 3 Ma ago.^[105] At least one genus of relatively small terror birds, Psilopterus, appears to have survived to as recently as about 96,000 years ago.^[121][122]

The native carnivore guild appears to have collapsed completely roughly 3 Ma ago (including the extinction of the last sparassodonts), not correlated with the arrival of carnivorans in South America, with terrestrial carnivore diversity being low thereafter.^[105][123] This has been suggested to have opened up ecological niches and allowed carnivorans to establish themselves in South America due to low competition.^{[114][124][125]} A meteor impact 3.3 million years ago in southern South America has been suggested as a possible cause of this turnover, but this is still controversial.^[126][123] A similar pattern occurs in the crocodilian fauna, where modern crocodiles (Crocodylus) dispersed to South America during the Pliocene and became the dominant member of crocodilian communities after the late Miocene extinction of the previously dominant large native crocodilians such as the giant caiman Purussaurus and giant gharial Gryposuchus, which is thought to be related to the loss of wetlands habitat across northern South America.^[127][128]

Whether this revised scenario with a reduced role for competitive exclusion applies to other groups of South American mammals such as notoungulates and litopterns is unclear, though some authors have pointed out a protracted decline in South American native ungulate diversity since the middle Miocene.^[129] Regardless of how this turnover happened, it is clear that carnivorans benefitted from it. Several groups of carnivorans such as dogs and cats underwent an adaptive radiation in South America after dispersing there, and the greatest modern diversity of canids in the world is in South America.^[99]

The eventual triumph of the Nearctic migrants was ultimately based on geography, which played into the hands of the northern invaders in two crucial respects. The first was a matter of climate. Any species that reached Panama from either direction obviously had to be able to tolerate moist tropical conditions. Those migrating southward would then be able to occupy much of South America without encountering climates that were markedly different. However, northward migrants would have encountered drier or cooler conditions by the time they reached the vicinity of the Trans-Mexican Volcanic Belt. The challenge this climatic asymmetry (see map on right) presented was particularly acute for Neotropic species specialized for tropical rainforest environments, which had little prospect of penetrating beyond Central America. As a result, Central America currently has 41 mammal species of Neotropical origin,^{[n 18]} compared to only three for temperate North America. However, species of South American origin (marsupials, xenarthrans, caviomorph rodents, and monkeys) still comprise only 21% of species from nonflying, nonmarine mammal groups in Central America, while North American invaders constitute 49% of species from such groups in South America. Thus, climate alone cannot fully account for the greater success of species of Nearctic origin during the interchange.

The second and more important advantage geography gave to the northerners is related to the land area in which their ancestors evolved. During the Cenozoic, North America was periodically connected to Eurasia via Beringia, allowing repeated migrations back and forth to unite the faunas of the two continents.^{[n 19]} Eurasia was connected in turn to Africa, which contributed further to the species that made their way to North America.^{[n 20]} South America, though, was connected only to Antarctica and Australia, two much smaller and less hospitable continents, and only in the early Cenozoic. Moreover, this land connection does not seem to have carried much traffic (apparently no mammals other than marsupials and perhaps a few monotremes ever migrated by this route), particularly in the direction of South America. This means that Northern Hemisphere species arose within a land area roughly six times greater than was available to South American species. North American species were thus products of a larger and more competitive arena,^{[n 21][88][130][131]} where evolution would have proceeded more rapidly. They tended to be more efficient and brainier,^{[n 22][n 23]} generally able to outrun and outwit their South American counterparts, who were products of an evolutionary backwater. In the cases of ungulates and their predators, South American forms were replaced wholesale by the invaders, possibly a result of these advantages.

The greater eventual success of South America's African immigrants compared to its native early Cenozoic mammal fauna is another example of this phenomenon, since the former evolved over a greater land area; their ancestors migrated from Eurasia to Africa, two significantly larger continents, before finding their way to South America.^[58]

Against this backdrop, the ability of South America's xenarthrans to compete effectively against the northerners represents a special case. The explanation for the xenarthrans' success lies in part in their idiosyncratic approach to defending against predation, based on possession of body armor or formidable claws. The xenarthrans did not need to be fleet-footed or quick-witted to survive. Such a strategy may have been forced on them by their low metabolic rate (the lowest among the therians).^[139][140] Their low metabolic rate may in turn have been advantageous in allowing them to subsist on less abundant^[141] or less nutritious food sources. Unfortunately, the defensive adaptations of the large xenarthrans would have offered little protection against humans armed with spears and other projectiles.

At the end of the Pleistocene epoch, about 12,000 years ago, three dramatic developments occurred in the Americas at roughly the same time (geologically speaking). Paleoindians invaded and occupied the New World (although humans may have been living in the Americas, including what is now the southern US and Chile, more than 15,000 years ago^[142]), the last glacial period came to an end, and a large fraction of the megafauna of both North and South America went extinct. This wave of extinctions swept off the face of the Earth many of the successful participants of the GABI, as well as other species that had not migrated.

All the pampatheres, glyptodonts, ground sloths, equids, proboscideans,^{[143][144][83]} giant short-faced bears, dire wolves, and machairodont species of both continents disappeared. The last of the South and Central American notoungulates and litopterns died out, as well as North America's giant beavers, lions, dholes, cheetahs, and many of its antilocaprid, bovid, cervid, tapirid and tayassuid ungulates. Some groups disappeared over most or all of their original range, but survived in their adopted homes, e.g. South American tapirs, camelids, and tremarctine bears (cougars and jaguars may have been temporarily reduced to South American refugia also). Others, such as capybaras, survived in their original range, but died out in areas to which they had migrated. Notably, this extinction pulse eliminated all Neotropic migrants to North America larger than about 15 kg (the size of a big porcupine), and all native South American mammals larger than about 65 kg (the size of a big capybara or giant anteater). In contrast, the largest surviving native North American mammal, the wood bison, can exceed 900 kg (2,000 lb), and the largest surviving Nearctic migrant to South America, Baird's tapir, can reach 400 kg (880 lb).

The near-simultaneity of the megafaunal extinctions with the glacial retreat and the peopling of the Americas has led to proposals that both climate change and human hunting played a role.^[94] Although the subject is contentious,^{[145][146][147][148][149]} a number of considerations suggest that human activities were pivotal.^[95][150] The extinctions did not occur selectively in the climatic zones that would have been most affected by the warming trend, and no plausible general climate-based megafauna-killing mechanism could explain the continent-wide extinctions. The climate change took place worldwide, but had little effect on the megafauna in Africa and southern Asia, where megafaunal species had coevolved with humans. Numerous very similar glacial retreats had occurred previously within the ice age of the last several million years without ever producing comparable waves of extinction in the Americas or anywhere else.

Similar megafaunal extinctions have occurred on other recently populated land masses (e.g. Australia,^[151][152] Japan,^[153] Madagascar,^[154] New Zealand,^[155] and many smaller islands around the world, such as Cyprus,^[156] Crete, Tilos and New Caledonia^[157]) at different times that correspond closely to the first arrival of humans at each location. These extinction pulses invariably swept rapidly over the full extent of a contiguous land mass, regardless of whether it was an island or a hemisphere-spanning set of connected continents. This was true despite the fact that all the larger land masses involved (as well as many of the smaller ones) contained multiple climatic zones that would have been affected differently by any climate changes occurring at the time. However, on sizable islands far enough offshore from newly occupied territory to escape immediate human colonization, megafaunal species sometimes survived for many thousands of years after they or related species became extinct on the mainland; examples include giant kangaroos in Tasmania,^[158][159] giant Chelonoidis tortoises of the Galápagos Islands (formerly also of South America^[94]), giant Dipsochelys tortoises of the Seychelles (formerly also of Madagascar), giant meiolaniid turtles on Lord Howe Island, New Caledonia and Vanuatu (previously also of Australia),^{[160][n 24]} ground sloths on the Antilles,^[163][164] Steller's sea cows off the Commander Islands^[165] and woolly mammoths on Wrangel Island^[166] and Saint Paul Island.^[167]

The glacial retreat may have played a primarily indirect role in the extinctions in the Americas by simply facilitating the movement of humans southeastward from Beringia to North America. The reason that a number of groups went extinct in North America but lived on in South America (while no examples of the opposite pattern are known) appears to be that the dense rainforest of the Amazon basin and the high peaks of the Andes provided environments that afforded a degree of protection from human predation.^{[168][n 25][n 26]}

Extant or extinct (†) North American taxa whose ancestors migrated out of South America and reached the modern territory of the contiguous United States:^{[n 27]}

Fish

• Cichlids (Cichlidae: e.g. Texas cichlid) – freshwater fish that often tolerate brackish conditions

Amphibians

• Bufonid toads (Bufo)^[169][170]
• Hylid frogs^[171]
• Leptodactylid frogs^[172] – as far north as Texas
• Microhylid frogs^[169]

Birds

• Parrots (Neotropical parrots: thick-billed parrot, †Carolina parakeet)
• †Terror birds (Phorusrhacidae: Titanis walleri)
• Tanagers (Thraupidae)^[173][174]
• Hummingbirds (Trochilidae)
• Suboscine birds (Tyranni):
  • Tityras and allies (Tityridae): rose-throated becard
  • Tyrant flycatchers (Tyrannidae)^[173]

Mammals

• Virginia opossum (Didelphis virginiana)
• Xenarthrans (Xenarthra)
  • Armadillos (nine-banded armadillo Dasypus novemcinctus, †D. bellus)
  • †Pachyarmatherium leiseyi, an enigmatic armored armadillo relative
  • †Pampatheres (Plaina,^[175] Holmesina) – large armadillo-like animals
  • †Glyptodonts (Glyptotherium)
  • †Megalonychid ground sloths (Pliometanastes, Megalonyx)
  • †Megatheriid ground sloths (Eremotherium)
  • †Mylodontid ground sloths (Thinobadistes, Glossotherium,^[175] Paramylodon)
  • †Nothrotheriid ground sloths (Nothrotheriops, Nothrotherium)
• Rodents (Rodentia)
  • New World porcupines (Erethizon dorsatum, †Erethizon poyeri, †E. kleini)
  • Capybaras (†Neochoerus pinckneyi, †N. aesopi)
• †Mixotoxodon – a rhino-sized toxodontid notoungulate^{[n 28]}
• Cougar (Puma concolor) – returning from a South American refugium after North American cougars were extirpated in the Pleistocene extinctions^[178]
• Bats (Chiroptera)
  • Molossid bats^[59]
  • Mormoopid bats (Mormoops megalophylla)^[60]
  • Vampire bats (†Desmodus stocki, †D. archaeodaptes)

• 
  Gray tree frog, Hyla versicolor
• 
  Nine-banded armadillo, Dasypus novemcinctus
• 
  The pampathere †Holmesina septentrionalis
• 
  The glyptodont †Glyptotherium
• 
  The megatheriid ground sloth †Eremotherium
• 
  The toxodontid †Mixotoxodon

Extant or extinct (†) North American taxa whose ancestors migrated out of South America, but failed to reach the contiguous United States and were confined to Mexico and Central America:^{[n 27][n 29]}

Invertebrates

• Gonyleptid harvestmen (Opiliones: Gonyleptidae)

Fish

• Electric knifefishes (Gymnotiformes)
• Hoplosternum punctatum – an armored catfish (Siluriformes: Callichthyidae)
• Several species of loricariid catfish (Siluriformes: Loricariidae)

Amphibians

• Caeciliid caecilians (Caecilia, Oscaecilia) – snake-like amphibians, Panama and Costa Rica only^[179]
• Poison dart frogs (Dendrobatidae)^[180]

Reptiles

• Boine boas (Boidae: Boinae)
• Spectacled caiman (Caiman crocodilus)^[181]
• †Purussaurus^[182] – giant caimans

Birds

• Great curassow (Crax rubra)^[183]
• Toucans (Ramphastidae)
• Tinamous (Tinamidae)
• Additional suboscine birds (Tyranni):
  • Gnateaters (Conopophagidae)^[173]
  • Cotingas (Cotingidae)^[173]
  • Ground antbirds (Formicariidae)^[173]
  • Ovenbirds and woodcreepers (Furnariidae)^[184]
  • Antpittas (Grallariidae)^[173]
  • Manakins (Pipridae)^[173]
  • Tapaculos (Rhinocryptidae)^[173]
  • Antbirds (Thamnophilidae)^[173]
  • Other Neotropical parrots (Arinae)

Mammals

• Other opossums (Didelphidae) – 11 additional extant species^{[n 18]}
• Xenarthrans (Xenarthra)
  • Northern naked-tailed armadillo (Cabassous centralis)
  • Three-toed sloths (Bradypodidae: Bradypus variegatus, B. pygmaeus)
  • Hoffmann's two-toed sloth (Choloepodidae: Choloepus hoffmanni)
  • †Scelidotheriid ground sloths (Scelidotherium, found in Panama^[185])
  • Silky anteater (Cyclopedidae: Cyclopes dorsalis)
  • Other anteaters (Myrmecophagidae: Myrmecophaga tridactyla,^{[n 30]} Tamandua mexicana)
• Rodents (Rodentia)
  • Rothschild's and Mexican hairy dwarf porcupines (Coendou rothschildi, Sphiggurus mexicanus)
  • Other caviomorph rodents (Caviomorpha) – 9 additional extant species^{[n 18]}
• Platyrrhine monkeys (Platyrrhini) – at least 8 extant species^{[n 18][n 31]}
• Carnivorans (Carnivora)
  • Olingos (Bassaricyon) – thought to have arisen in the Andes of northwest South America after their procyonid ancestors invaded from the north, before diversifying and migrating back to Central America^[188]
  • South American short-faced bears (Tremarctinae: †Arctotherium wingei) – thought to have invaded to as far as the Yucatán after arising in South America from North American ancestors^[189]
  • South American canids (Caninae: †Protocyon troglodytes) – thought to have invaded to as far as the Yucatán after arising in South America from North American ancestors^[189]
• Bats (Chiroptera)
  • Emballonurid bats^[61]
  • Furipterid bats^[60] (Furipterus horrens)
  • Other mormoopid bats^[60]
  • Noctilionid bats^[60] (Noctilio albiventris, Noctilio leporinus)
  • Other phyllostomid bats,^[60] including all 3 extant vampire bat species (Desmodontinae)
  • Thyropterid bats^[60] (Thyroptera discifera, Thyroptera tricolor)

• 
  Strawberry poison-dart frog, Oophaga pumilio
• 
  Spectacled caiman, Caiman crocodilus
• 
  The two-toed sloth Choloepus hoffmanni
• 
  Central American agouti, Dasyprocta punctata
• 
  White-headed capuchin, Cebus capucinus
• 
  Great tinamou, Tinamus major

Extant or extinct (†) South American taxa whose ancestors migrated out of North America:^{[n 27]}

Amphibians

• Dermophiid caecilians (Dermophis glandulosus) – only present in northwestern Colombia^[190]
• Lungless salamanders^{[n 32][179]} (Bolitoglossa,^[191][192] Oedipina) – only present in northern South America
• Ranid frogs^[169] – only present in northern South America

Reptiles

• Turtles (Testudines)
  • Chelydrid (snapping) turtles (Chelydra acutirostris) – only present in northwestern South America
  • Emydid (pond) turtles (Trachemys)
  • Geoemydid (wood) turtles (Rhinoclemmys)^[193] – only present in northern South America
• Snakes (Serpentes)
  • Coral snakes (Leptomicrurus, Micrurus)^[194][195]
  • South American rattlesnake (Crotalus durissus)^[196]
  • Lanceheads (Bothrops)
  • Bushmasters (Lachesis)
  • Other pit vipers (Bothriechis schlegelii, Bothriopsis, Porthidium)^[197]

Birds

• American sparrows (Emberizidae)^[173][198]
• Trogons (Trogon)^[199]
• Condors (Vultur gryphus, †Dryornis, †Geronogyps, †Wingegyps, †Perugyps)^{[200][201][202][n 33]}

Mammals

• Small-eared shrews (Cryptotis) – only present in NW South America: Colombia, Venezuela, Ecuador, Peru
• Rodents (Rodentia)
  • Geomyid pocket gophers (Orthogeomys thaeleri) – one species, in Colombia
  • Heteromyid mice (Heteromys) – only present in NW South America: Colombia, Venezuela, Ecuador
  • Cricetid – primarily sigmodontine – rats and mice (Cricetidae: Sigmodontinae) – the nonsigmodontines consist of two species present only in Colombia and Ecuador^{[n 34]}
  • Tree squirrels (Sciurus, Microsciurus, Sciurillus) – present in northern and central South America
• Cottontail rabbits (Sylvilagus brasiliensis, S. floridanus, S. varynaensis) – present in northern and central South America
• Odd-toed ungulates (Perissodactyla)
  • Tapirs (Tapirus bairdii, †T. cristatellus, T. pinchaque, †T. rondoniensis, T. terrestris)
  • Equids (Equus ferus, †Hippidion)^{[n 35]}
• Even-toed ungulates (Artiodactyla)
  • Peccaries (†Sylvochoerus,^[79] †Waldochoerus,^[79] Tayassu pecari, Catagonus wagneri, Dicotyles tajacu)
  • †Palaeomerycids (Surameryx^[80])
  • Deer (†Antifer, †Morenelaphus, †Agalmaceros, Odocoileus, Blastocerus, Ozotoceros, Mazama, Pudu, Hippocamelus)
  • Camelids (Lama guanicoe, Vicugna vicugna, †Eulamaops, †Hemiauchenia, †Palaeolama)
• †Gomphotheres (Cuvieronius hyodon, Notiomastodon^{[n 36]} platensis) – elephant relatives^[83]
• Carnivorans (Carnivora)
  • Otters (Lontra, Pteronura)
  • Other mustelids (Mustelinae: Eira, Galictis, Lyncodon, Neogale)
  • Hog-nosed skunks (Conepatus chinga, C. humboldtii, C. semistriatus)
  • Procyonids (Procyon, Nasua, Nasuella, Potos, Bassaricyon, †Cyonasua, †Chapalmalania)
  • Short-faced bears (Tremarctinae: Tremarctos ornatus, †Arctotherium)^[206]
  • Wolves (†Canis gezi, †C. nehringi, †A. dirus – the latter known only from as far south as southern Bolivia^[207])^[208][209]
  • Gray fox^{[n 37]} (Urocyon cinereoargenteus) – only present in NW South America: Colombia, Venezuela
  • Other canids (†Dusicyon,^[210][211] †Theriodictis, †Protocyon, Atelocynus, Cerdocyon, Lycalopex, Chrysocyon, Speothos)
  • Small felids (Leopardus) – all 9 extant species (e.g. L. pardalis, L. wiedii)
  • Cougar (Puma concolor) and jaguarundi (P. yagouaroundi)
  • Jaguar (Panthera onca)
  • †Scimitar cats (Xenosmilus, Homotherium) – known so far only from Uruguay^[212] and Venezuela^{[213][214][215]}
  • †Saber-toothed cats (Smilodon gracilis,^[215] S. fatalis,^[216] S. populator)
  • †American lion (Panthera leo atrox), reported from Peru^[217] and Argentina and Chile;^[218] however, the former set of remains has later been identified as belonging to a jaguar^[219] and the latter set of remains were initially identified as being from jaguars
• Bats (Chiroptera)
  • Natalid bats^[59] (Chilonatalus micropus, Natalus espiritosantensis, N. tumidirostris)
  • Vespertilionid bats^[59]

• 
  Amazonian palm viper, Bothrops bilineatus
• 
  Drymoreomys albimaculatus, a sigmodontine rodent
• 
  The camelid Lama guanicoe
• 
  †Cuvieronius, a gomphothere
• 
  The coati Nasua nasua
• 
  Saber-toothed †Smilodon populator

• Caribbean Plate § First American land bridge
• Central American Seaway
• Columbian Exchange
• List of mammals of the Caribbean
• List of mammals of Central America
• List of mammals of North America
• List of mammals of South America
• Lists of extinct animals by continent

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