Overview of the events of 2022 in science
This article lists a number of significant events in science that have occurred in the first quarter of 2022 .
3 January: OpenAlex, a free online index with metadata about over 200 million scientific documents is launched. The graphs visualize recent developments of science based on this data .[ 5]
10 January: The first successful xenogeneic heart transplant , from a genetically modified pig to a human patient, is reported.
3 January – OpenAlex, a free online index of over 200 million scientific documents – each with metadata such as sources, citations , author information and research topics – is launched. The API and open source website can be used for metascience , scientometrics and novel tools that query this semantic web of papers .[ 6] [ 7] [ 8]
5 January – Scientists show how antibiotic resistance also evolves naturally, without and before the use of antibiotics .[ 9] [ 10]
6 January
7 January – Progress in cancer pre-screening, screening and early detection is reported: metabolomic biomarkers in blood (4 J.),[ 17] [ 18] circulating protein biomarkers (7 J.),[ 19] [ 20] and an optical biopsy system with a fine-needle probe (6 J.).[ 21] [ 22]
10 January
11 January
The first known deformation of an exoplanet is detected by the CHEOPS mission, which finds that WASP-103b is being strongly influenced by its parent star's close proximity, making the planet shaped like an ellipsoid instead of a sphere.[ 29] [ 30]
A study reports the likely detection of an extreme SEP event that hit Earth ~9000 years ago and, unlike known Solar storms , unexpectedly happened near a Solar minimum .[ 31] [ 32]
12 January: The ~14 Myr old Local Bubble drives nearby young star formation.
12 January: Mutations are shown to not be random – frequency can vary between regions.
12 January
13 January
18 January
19 January: Antibiotic resistance contributed to ~5 M deaths in 2019 according to a first global assessment.
19 January
In a first global assessment, scientists report, based on medical records , that antibiotic resistance may have contributed to ~4.95 million deaths (1.3 M directly attributed) in 2019, more than e.g. AIDS.[ 50] [ 51] Increased antibiotic use during the COVID-19 pandemic may exacerbate this global health challenge.[ 52] [ 53]
A report recommends a number of measures such as, broadly described, building resilience to scientific misinformation and a healthy online information environment and not having offending content removed.[ 54]
20 January – UNESCO announces a major new coral reef off the coast of Tahiti , stretching 3 km and in "pristine" condition, discovered by marine biologists as part of the Seabed 2030 Project .[ 55] [ 56]
22 January – According to a space monitoring company, a Chinese satellite, SJ-21, grabs an unused satellite and throws it into an orbit with a lower risk for the space debris to collide.[ 57] [ 58]
24 January
25 January
26 January
31 January – Researchers find evidence that reading on electronic devices can reduce comprehension . Reading text on a smartphone was found to promote overactivity in the prefrontal cortex and reduce sighing frequency compared to reading text on paper.[ 84] [ 85]
9 February: A new test at the Joint European Torus achieves a breakthrough of more than twice (59 M J) the previous fusion energy generation record set in 1997.
14 February: The most comprehensive study of pharmaceutical pollution of the world's rivers is published.
28 February: A study shows annual carbon emissions (or carbon loss) from tropical deforestation have doubled during the last two decades and continue to increase.
1 March
2 March – Researchers report the development of a system that combines the MOST solar thermal energy storage system with a chip-sized thermoelectric generator to generate electricity from it.[ 176] [ 177]
4 March – A study using brain-scans of 36,678 UK Biobank participants shows that negative associations between alcohol intake and brain macrostructure and microstructure are apparent in individuals consuming an average of "one to two daily alcohol units" that some may consider light or moderate consumption.[ 178] [ 179] A study of 371,463 UK Biobank participants' cardiovascular health published on 25 March shows that while "light to moderate alcohol consumption was associated with healthier lifestyle factors" than in alcohol-abstainers, adjustment for such factors suggests that in principle minimizing alcohol intake could lower risks for (or negative effects towards) hypertension and coronary artery disease for everybody.[ 180] [ 181]
7 March
Pig calls are decoded into positive or negative emotions, using an algorithm based on ~7,000 audio recordings classified by an artificial neural network for potential use in farms .[ 182] [ 183]
A new cellular rejuvenation therapy of bursts of iPSC reprogramming is reported, which can reverse aspects of aging in mice, without causing cancer or other health problems.[ 184] [ 185]
Researchers report that more than three-quarters of the Amazon rainforest has been losing resilience due to deforestation and climate change since the early 2000s as measured by recovery-time from short-term perturbations ("critical slowing down" (CSD)), reinforcing the theory that it is approaching a critical transition .[ 186] [ 187] On March 11, INPE reports satellite data that show record-high levels of Amazon deforestation in Brazil for a February (199 km²).[ 188]
Scientists report how COVID-19 impacts the brain at least temporarily based on brain-scans and cognitive tests of 785 UK Biobank participants (401 positive cases), including grey matter thickness- and brain size -reductions.[ 189] [ 190]
Researchers report the first artificial parthenogenesis in mammals (viable mice offspring born from unfertilized eggs).[ 191] [ 192]
A study suggests that half of the US population has been exposed to substantially detrimental lead levels in early childhood – mainly from car exhaust whose lead pollution peaked in the 1970s.[ 193] [ 194] [United States-centric ]
Researchers report the development of 3D-printed nano -"skyscraper" electrodes that house cyanobacteria for extracting substantially more sustainable bioenergy from their photosynthesis than before.[ 195] [ 196]
Researchers report that the widely used supplements glycine and NAC when combined as "GlyNAC", which previously showed various beneficial effects in humans i.a. in a small trial by the authors,[ 197] can extend lifespan by 24% in mice when taken at old age.[ 198] [ 199]
Progress in biomarkers -based cancer screening is reported: researchers estimate risks for prostate cancer based on age, PSA and hK2 (7 Mar).[ 200] [ 201] Researchers achieve high prediction accuracy for pancreatic cancer using faecal microbiota biomarkers (8 Mar).[ 202] [ 203] A cancer test that checks for more mutations than ever before in one tissue sample is launched by a biotech-company (15 Mar).[ 204] The first clinical test of a technology to detect early-stage cancer via novel[ 205] biomarkers of extracellular vesicles concludes with promising results, possibly reaching screening-relevant sensitivities at high specificity at least for pancreatic cancer (17 Mar).[ 206] [ 207]
Using drug discovery artificial intelligence algorithms, researchers generate 40,000 potential chemical weapon candidates,[ 208] [ 209] which may be relevant to timely regulation of chemicals and related products that can be used to manufacture the fraction of viable candidates and either illustrates or proves that such software is dual-use technology .[citation needed ]
8 March – Researchers report SARS-CoV-2 variant recombinant viruses that contain elements of Delta and Omicron – Deltacron (also called "Deltamicron").[ 210] [ 211] [ 212] Recombination occurs when a virus combines parts from a related virus with its genetic sequence as it assembles copies of itself. It is unclear whether Deltacron – which is not to be confused with "Deltacron" reported in January – will be able to compete with Omicron and whether that would be detrimental to health.[ 213]
9 March
Researchers in the Antarctic announce they have found Endurance , one of the greatest ever undiscovered shipwrecks , which sank in 1915 during Ernest Shackleton 's exploration.[ 214]
Doctors report that an antiseptic drug reduced recurring urinary tract infections in a trial as effectively as antibiotics whose prevalent use is implicated in antimicrobial resistance .[ 215] [ 216]
Researchers report that, on average, played "a leading role in driving up GHG emissions in the past decade and are on the way to becoming the largest contributor " due to factors such as demographic transition , and high expenditures on carbon-intensive products like energy which is used i.a. for heating rooms and private transport.[ 217] [ 218]
Results from a study imply "that all cells probably possess a common mechanism of [methane] formation ". This universal mechanism is based on interactions among ROS , iron and methyl donors .[ 219] [ 220] [ 221]
Scientists demonstrate limits and the scale of challenge of genetic-editing-based de-extinction , suggesting resources spent on more comprehensive de-extinction such as of the woolly mammoth may currently not be well allocated and substantially limited.[ 222] [ 223]
Using graphene and molybdenum disulfide , Chinese scientists create a transistor gate with a length of 0.34 nm, equivalent to just one carbon atom, by exploiting the vertical aspect of the device.[ 224] [ 225]
10 March
A study estimates that "relocating current croplands to [environmentally] optimal locations, whilst allowing ecosystems in then-abandoned areas to regenerate , could simultaneously decrease the current carbon, biodiversity, and irrigation water footprint of global crop production by 71%, 87%, and 100%", with relocation only within national borders also having substantial potential.[ 226] [ 227]
A study reports that excess mortality data suggests that between Jan 1, 2020, and Dec 31, 2021, ~18.2 million people died worldwide because of the COVID-19 pandemic (compared to 5.94 million reported deaths). It notes that further research could help distinguish the proportions directly caused by COVID-19 from those caused by indirect consequences of the pandemic.[ 228] [ 229]
11 March – Researchers demonstrate electrostatic dust removal from solar panels .[ 230] [ 231]
12 March – Biomedical gerontologists demonstrate a mechanism of anti-aging senolytics , in particular of Dasatinib plus Quercetin (D+Q) – an increase of α-Klotho as shown in mice, human cells and in a human trial .[ 232] [ 233]
14 March – Impact and reactions to the 2022 Russian invasion of Ukraine in science: at least one journal enacts a immediate publishing boycotts against Russia-located researchers or institutions (before 14 Mar).[ 234] Researchers caution that a surge of various diseases is to be expected due to the war (15 Mar).[ 235] Scientists warn that policy-makers should not abandon sustainable farming practices to increase grain production in response to resulting food insecurity , but change "the demand side which can lead to both a more resilient and more sustainable global food system " (18 Mar)[ 236] – such as limiting the import of animal feed (10 Mar)[ 237] – and e.g. expanding wheat production in high-productivity areas (22 Mar).[ 238] Scientists explain why the Ukraine biolabs conspiracy theory is disinformation (11 Mar).[ 239] Scientists describe dangers of nuclear energy facilities within war-zones and bombing/shelling of or near them – as well as of waste-sites [ 240] – by Russia.[ 241] [ 242]
15 March – Neuroscientists report that mutations that enable people to naturally sleep as short as five hours reduce Alzheimer's pathology in mice.[ 243] [ 244] On 17 March, a study reports that longer and more frequent daytime naps appears to be associated with higher risk of Alzheimer's dementia.[ 245] [ 246]
16 March
18 March
21 March
The number of confirmed exoplanets exceeds 5,000.[ 255]
Before formal publication of the 'Global Carbon Budget 2021' preprint ,[ 256] scientists report, based on Carbon Monitor[ 257] data, that after COVID-19-pandemic-caused record-level declines in 2020, global CO2 emissions rebounded sharply by 4.8% in 2021, indicating that at the current trajectory, the 1.5 °C carbon budget would be used up within 9.5 years with a ⅔ likelihood.[ 258]
24 March: Scientists describe and quantify the biophysical mechanisms by which forests influence climate.
23 March – A far-UVC (ultraviolet light) air purification system is demonstrated by scientists, which can reduce levels of an airborne pathogen by 98% within minutes. This is equivalent to 184 air changes per hour – better than HEPA air cleaners – and is proposed as a solution for COVID-19 and other future pandemics.[ 259] [ 260] On 9 March, a study reports promising results of tests of durably biocide treated air filters for preventing the spread of airborne pathogens like SARS-CoV-2 , including of field trials onboard public rail transport .[ 261] [ 262]
24 March
A physical speed limit for electronic computers, optoelectronics , of approximately one petahertz (1015 Hz) is reported. This theoretical maximum is about 100,000 times faster than modern transistors.[ 263] [ 264]
Scientists review the biophysical mechanisms by which forests influence climate, showing that beyond 50°N large scale deforestation leads to a net global cooling, that tropical deforestation leads to warming , and that as well as how standing tropical forests help cool the average global temperature by more than 1 °C.[ 265] [ 266]
Researchers report the development of the first prototype, photonic, for neuromorphic (quantum-)computers /artificial neural networks .[ 267] [ 268]
25 March – Genetic engineers report field test results that show CRISPR -based gene knockout of KRN2 in maize and OsKRN2 in rice increased grain yields by ~10% and ~8% and did not find any negative effects.[ 269] [ 270]
30 March – WHL0137-LS , also known as Earendel, is reported as the farthest individual star ever discovered, its light having taken 12.9 billion years to reach Earth.[ 271] [ 272]
31 March
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^ "Blood test helps predict who may benefit from lung cancer screening: Prediction model with blood test significantly improves lung cancer risk assessment compared to current guidelines" . ScienceDaily . Retrieved 14 February 2022 .
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^ "Optical biopsy system aims to improve liver cancer diagnosis" . Physics World . 1 February 2022.
^ Zherebtsov, Evgenii A.; Potapova, Elena V.; Mamoshin, Andrian V.; Shupletsov, Valery V.; Kandurova, Ksenia Y.; Dremin, Viktor V.; Abramov, Andrey Y.; Dunaev, Andrey V. (1 February 2022). "Fluorescence lifetime needle optical biopsy discriminates hepatocellular carcinoma" . Biomedical Optics Express . 13 (2): 633–646. doi :10.1364/BOE.447687 . PMC 8884204 . PMID 35284175 .
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^ "Cheops reveals a rugby ball-shaped exoplanet" . ESA . 11 January 2022. Archived from the original on 11 January 2022. Retrieved 12 January 2022 .
^ Barros, S. C. C.; Akinsanmi, B.; Boué, G.; et al. (1 January 2022). "Detection of the tidal deformation of WASP-103b at 3 σ with CHEOPS". Astronomy & Astrophysics . 657 : A52. arXiv :2201.03328 . Bibcode :2022A&A...657A..52B . doi :10.1051/0004-6361/202142196 . ISSN 0004-6361 . S2CID 244757273 .
^ "Ancient ice reveals mysterious solar storm" . Lund University . Retrieved 14 February 2022 .
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^ "Fastest DNA sequencing technique helps undiagnosed patients find answers in mere hours" . Stanford . 12 January 2022. Archived from the original on 22 January 2022. Retrieved 23 January 2022 .
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^ "Study challenges evolutionary theory that DNA mutations are random" . U.C. Davis . Retrieved 12 February 2022 .
^ Monroe, J. Grey; Srikant, Thanvi; Carbonell-Bejerano, Pablo; Becker, Claude; Lensink, Mariele; Exposito-Alonso, Moises; Klein, Marie; Hildebrandt, Julia; Neumann, Manuela; Kliebenstein, Daniel; Weng, Mao-Lun; Imbert, Eric; Ågren, Jon; Rutter, Matthew T.; Fenster, Charles B.; Weigel, Detlef (February 2022). "Mutation bias reflects natural selection in Arabidopsis thaliana" . Nature . 602 (7895): 101–105. Bibcode :2022Natur.602..101M . doi :10.1038/s41586-021-04269-6 . ISSN 1476-4687 . PMC 8810380 . PMID 35022609 .
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^ Zucker, Catherine; Goodman, Alyssa A.; Alves, João; Bialy, Shmuel; Foley, Michael; Speagle, Joshua S.; Großschedl, Josefa; Finkbeiner, Douglas P.; Burkert, Andreas; Khimey, Diana; Swiggum, Cameren (January 2022). "Star formation near the Sun is driven by expansion of the Local Bubble". Nature . 601 (7893): 334–337. arXiv :2201.05124 . Bibcode :2022Natur.601..334Z . doi :10.1038/s41586-021-04286-5 . ISSN 1476-4687 . PMID 35022612 . S2CID 245906333 .
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^
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^ Fuller, Carl W.; Padayatti, Pius S.; Abderrahim, Hadi; Adamiak, Lisa; Alagar, Nolan; Ananthapadmanabhan, Nagaraj; Baek, Jihye; Chinni, Sarat; Choi, Chulmin; Delaney, Kevin J.; Dubielzig, Rich; Frkanec, Julie; Garcia, Chris; Gardner, Calvin; Gebhardt, Daniel; Geiser, Tim; Gutierrez, Zachariah; Hall, Drew A.; Hodges, Andrew P.; Hou, Guangyuan; Jain, Sonal; Jones, Teresa; Lobaton, Raymond; Majzik, Zsolt; Marte, Allen; Mohan, Prateek; Mola, Paul; Mudondo, Paul; Mullinix, James; Nguyen, Thuan; Ollinger, Frederick; Orr, Sarah; Ouyang, Yuxuan; Pan, Paul; Park, Namseok; Porras, David; Prabhu, Keshav; Reese, Cassandra; Ruel, Travers; Sauerbrey, Trevor; Sawyer, Jaymie R.; Sinha, Prem; Tu, Jacky; Venkatesh, A. G.; VijayKumar, Sushmitha; Zheng, Le; Jin, Sungho; Tour, James M.; Church, George M.; Mola, Paul W.; Merriman, Barry (1 February 2022). "Molecular electronics sensors on a scalable semiconductor chip: A platform for single-molecule measurement of binding kinetics and enzyme activity" . Proceedings of the National Academy of Sciences . 119 (5). Bibcode :2022PNAS..11912812F . doi :10.1073/pnas.2112812119 . ISSN 0027-8424 . PMC 8812571 . PMID 35074874 .
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