This is a list of notable alumni of Denison University in Granville, Ohio.
- Susan Campbell Baldridge - psychologist; Provost, Middlebury College
- Cynthia Baum – clinical psychologist and academic administrator
- David H. Bayley - pioneer in policing research and former Distinguished Professor Emeritus, School of Criminal Justice, SUNY Albany
- William G. Bowen - former President of Princeton University, current President of the Andrew W. Mellon Foundation
- Douglas A. Boyd - folklorist, oral historian, podcast host, and author, current director of the Louie B. Nunn Center for Oral History
- Richard Brandt - professor of philosophy, Swarthmore College and University of Michigan
- David G. Brown - university administrator (provost, chancellor, and president)
- Ernest DeWitt Burton - biblical scholar
- George Cressey - geographer, author, and academic
- Frederick German Detweiler - sociologist
- George Amos Dorsey - ethnographer
- Lottie Estelle Granger - president, Iowa State Teachers' Association
- Stephen Holmes - Walter E. Meyer Professor of Law, New York University
- John S. Lowe - professor and expert in energy law
- Roger H. Martin - 14th president of Randolph-Macon College
- Jeffrey Masten - Shakespeare and sexuality studies scholar, Northwestern University; Guggenheim fellow
- Kirtley F. Mather - geologist; professor and department chairman at Harvard University; civil libertarian and author
- Thomas Skidmore - historian and scholar specialized in Brazilian history
- Maria Tatar - John L. Loeb Professor of Germanic Languages and Literatures; Chair of the Committee on Degrees in Folklore and Mythology at Harvard University
- Stephen Tuttle - musicologist and former chairman of the department of music at the University of Virginia
Arts and Entertainment
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- Susan V. Booth - Artistic Director, Alliance Theatre, Atlanta; Artistic Director, Goodman Theatre, Chicago
- Steve Carell - screen and television actor
- Roe Conn - radio personality, WLS 890AM, Chicago
- Tom Cotter - comedian
- Franklin Cover - stage, screen and television actor
- Luke Ebbin - Grammy nominated record producer, songwriter and composer
- John Davidson - stage and television actor; game show host, including Hollywood Squares
- Jennifer Garner - screen and television actress
- Kyle Gordon - comedian
- Jeffrey Hatcher - playwright and screenwriter
- Hal Holbrook - stage, screen and television actor, known for portrayal of Mark Twain
- John Jeffcoat - screenwriter and film director, known for Outsourced
- Ademir Kenović - film director and producer
- Nancy Lynn - acrobatic pilot, killed in 2006 Culpeper Airfest crash
- Ann Magnuson - actress, performance artist, and nightclub performer
- John Malm Jr. - former manager of Trent Reznor and his band Nine Inch Nails
- Daniel Meyer - conductor and musical director
- Alex Moffat - actor and comedian
- P-Star (Priscilla Diaz) - rapper, actress, singer, model, director, DJ
- Hollis Resnik - singer and actress
- José Rivera - first Puerto Rican screenwriter to be nominated for an Academy Award
- John Schuck - screen, stage, and television actor
- Kurt Vincent, director of The Lost Arcade
- Andrew Levitt, drag queen known as Nina West
- Chase Hilt, Good Mythical Morning Producer.
- Chelsey Warner, Associate Producer - The Boys, Amazon
- Richard B. Austin - judge, United States District Court for the Northern District of Illinois
- Ruth Sarles Benedict - anti-war activist, researcher and journalist[1]
- John T. Chain, Jr. - retired U.S. Air Force General
- Robert Dold - U.S. Representative for Illinois's 10th congressional district
- Edmund Burke Fairfield - minister, educator, and politician, including 12th Lieutenant Governor of Michigan
- Carty Finkbeiner - former mayor of Toledo, Ohio
- Tony P. Hall - United States Ambassador to the United Nations Agencies for Food and Agriculture and United States Representative from Ohio
- Andrew S. Hanen - judge, United States District Court for the Southern District of Texas
- Judson Harmon - 45th Governor of Ohio and 41st United States Attorney General
- Leonard D. Heaton - former Surgeon General of the United States Army
- Edgar Winters Hillyer - judge, United States District Court for the District of Nevada
- Douglas Holtz-Eakin - former Director of the Congressional Budget Office and former chief economic policy adviser to U.S. Senator John McCain's 2008 presidential campaign
- Randy Hopper - former member of the Wisconsin State Senate
- Sue W. Kelly - former member of the United States Congress from New York
- Robert W. Levering - former United States Congressman
- Richard Lugar - United States Senator from Indiana; on the Board of Trustees
- Kenneth E. Melson - former ATF director
- Jim Petro - former Ohio Attorney General
- Jane Pringle - Member of the Maine House of Representatives
- Lewis A. Sachs - former US Assistant Secretary of the Treasury
- A. W. Sheldon - Associate Justice, Arizona Territorial Supreme Court
- Erastus B. Tyler - Union Army general in the American Civil War
- H. Clay Van Voorhis - former US Congressman
- Ed Weber - former US Congressman
- Yu Tsune-chi - Chinese Ambassador to Italy and Spain, United Nations delegate who took part in the San Francisco Conference
- Allen Zollars - Justice of the Indiana Supreme Court