252 - North Coastal Plain region in the northeast corner of the state, containing the Outer Banks (split from 919 in 1998)
910 / 472 - South Coastal Plain region in the southeast corner of the state, including Wilmington (split from 919 in 1993; 472 created as overlay beginning on October 7, 2022)
336 / 743 - Piedmont Triad and the northwest Piedmont region (336 created in 1997 as split from 910; 743 created as overlay in 2015)
828 - Western & Mountainous region of the state (split from 704 in 1998)
919 / 984 - The Research Triangle metropolitan region (919 created in 1954 as split from 704; 984 created as overlay in 2011)