Maxim Isaev, a Soviet spy operating in Nazi Germany under the name Max Otto von Stierlitz, tasked with disrupting the secret negotiations aimed at forging a separate peace between Germany and the Western Allies and bringing Nazi personnel under the US aegis. Introduced in the "Isaev – Stierlitz" series of novels by Yulian Semyonov.
Qyburn, who holds the same position after Varys flees following the conclusion of A Storm of Swords.
Brynden Rivers, known as "Bloodraven", who held the position, as well as that of Hand of the King, in the prequel series Tales of Dunk and Egg.
Simon Illyan, head of ImpSec (Barrayaran Imperial Security) in the Vorkosigan Saga series.
X2, head of the secret service in Ibn-e-Safi's Imran Series novels. X2 is strict leader whose identity remains hidden from his team members and he makes contact with them on telephone or transmitter and at the same time he does all the field work along with his teammates being Ali Imran, a charming young man who looks like a moron and idiot by face. Due to his perfection in maintaining this dual personality, neither from his teammates, nor from his enemies could conclude that this Idiot Ali Imran could be the chief of secret service whose voice on a phone call could make his subordinate nervous.
Garik "Face" Loran, previously one of the lead characters in the X-wing series, was the last known director of Galactic Alliance Intelligence, the NRI's successor.
Jiraiya (Naruto), the spymaster for the Village Hidden in the Leaves.
Lieutenant Colonel Yuuki(Joker Game), A lieutenant colonel to the Imperial Japanese Army, and also a spymaster. He is the founder of D-Agency. He once worked as a spy and given the nickname "Demon Lord"
William Walden and David Estes, the former/deceased Director of the CIA and Director of the Counter-terrorism Center, respectively, during seasons 1–2 of Homeland (TV series); throughout seasons 3, Saul Berenson was the acting-Director of the CIA.
Phillip "Phil" Coulson, after announcing his plan to go undercover for a while, General Fury hands Coulson the 'toolbox', a small cube containing coordinates and a few other things, and appoints Coulson acting executive director of S.H.I.E.L.D., with a mandate to rebuild the organization from the ground up.
Malory Archer was the head of the International Secret Intelligence Service (ISIS) in the television series Archer.
Hiram Burrows is the Empire Spymaster in the game Dishonored, who later becomes the first Lord Regent, the main antagonist in the game.
Protagonist Corvo Attano becomes the Spymaster after Hiram Burrows is executed according to book Dishonored: The Corroded Man.
Caius Cosades is the Imperial Grand-Spymaster of the Blades (who are an order of the Emperor's secret agents and protectors) in Morrowind, who acts as a guide, mentor and supervisor of the player character.[8]