From Wikipedia - Reading time: 8 min
- Cesar Baena (born 1986), cross-country skier and former Guinness World Record holder.
- Jesús Bandrés (born 1991), professional tennis player.
- Juan Alfonso Baptista (born 1976), actor and model.
- Carlos Barreto (1976–1999), bantamweight boxer.
- Ysis Barreto (born 1980), judoka.
- Armando Becker (born 1966), basketball player.
- Andrés Bello (1781–1865), humanist, diplomat, poet, legislator, philosopher, educator and philologist.
- Baruj Benacerraf (1920–2011), shared the 1980 Nobel Prize in Physiology.
- Alejandra Benítez (born 1980), sabre fencer.
- Bob Bissonnette (1981–2016), ice hockey player.
- Alfonso Blanco (born 1986), professional boxer.
- Gregor Blanco (born 1983), professional baseball outfielder.
- Marvin Blanco (born 1988), athlete.
- Serge Blanco (born 1958), rugby union footballer.
- Manuel Blum (born 1938), computer scientist.
- Iginia Boccalandro (born 1961), athlete.
- Simón Bolívar (1783–1830), father of independence in South America.
- Jacobo Borges (born 1931), contemporary, neo-figurative Latin-American artist.
- Carlos Bravo (born 1973), fencer.
- Sergio Camacho (born 1973), judoka.
- Nelson Canache Jr. (born 1978), auto racing driver.
- Hersony Canelón (born 1988), professional track and road cyclist.
- Carlos Cañizales (born 1993), professional boxer.
- Alfonso Carrasquel (1926–2005), professional baseball player, coach, scout and manager.
- Teresa Carreño (1853–1917), pianist, soprano, composer, and conductor.
- Martín Carrillo (born 1983), football manager.
- Johnny Cecotto (born 1956), professional Grand Prix motorcycle racer and auto racer.
- Freddy Cedeño (born 1981), volleyball player.
- Judith Chacón (1986–2009), weightlifter.
- Rick Chartraw (born 1954), professional ice hockey defenseman.
- Julian Chela-Flores (born 1942), astrobiologist and physicist.
- Arsenio Chirinos (1934–2015), cyclist.
- Víctor Chirinos (born 1941), cyclist.
- Néstor Colmenares (born 1987), professional basketball player.
- Jacinto Convit (1913–2014), physician and scientist.
- Carlos Coste (born 1976), professional free diver.
- Carlos Crassus (1920–1984), sports shooter.
- Mauro Libi Crestani, business
- Francisco José Cróquer (1920–1955), sportscaster specialized in baseball and boxing.
- Carlos Cruz-Diez (1923–2019), visual artist.
- Eliana Cuevas, jazz singer, whose music blends jazz with Latin music.
- Danny Ocean (born 1992), singer, songwriter and record producer.
- Marielena Davila (born 1992), actress and singer.
- Majandra Delfino (born 1981), actress and singer.
- Carlos Delgado Chalbaud (1909–1950), military officer.
- Daniel Dhers (born 1985), professional BMX rider.
- Antonio Díaz (born 1980), karateka.
- Oscar D'León (born 1943), musician and bassist best known for his work with salsa music.
- Franco de Vita (born 1954), singer, pianist and composer
- Ramon Domínguez (born 1976), champion jockey and Hall of Fame member in American thoroughbred horse racing.
- Kimberly Dos Ramos (born 1992), actress.
- Milka Duno (born 1972), race car driver.
- Rafael Duran (born 1938), wrestler.
- Alessandro Famularo (born 2003), racing driver
- Sebastián Fernández (born 2000), racing driver
- Silvio Fernández (fencer born 1946) (born 1946), fencer
- Silvio Fernández (fencer born 1979) (born 1979), épée fencer
- Stefanía Fernández (born 1990), journalist, model and beauty queen who won the Miss Venezuela 2008 and Miss Universe 2009 titles
- José Manuel Flores Sánchez (born 1986), model, Mister Venezuela 2009
- Tony Franco (born 1981), football manager
- Ramón Fumadó (born 1981), diver
- Germán Gabriel (born 1980), professional basketball player
- Andrés Galarraga (born 1961), professional baseball player
- Anaida Galindo (born 1987), political staffer, online magazine publisher, and the wife of Conservative Party of Canada leader Pierre Poilievre
- Rómulo Gallegos (1884–1969), novelist and politician
- Alex García (born 1977), stock car racing driver, and a former competitor in the NASCAR Nationwide Series
- Freddy García (born 1976), professional baseball pitcher
- Luis Alberto García (born 1980), taekwondo practitioner
- Yusmely García (born 1983), hurdler
- Mikael Gayme (born 1979), alpine skier
- Alejandra Ghersi (born 1989), musician and record producer
- Tomás Gil (born 1977), professional track and road cyclist
- Alejandro Gómez (born 1985), swimmer
- Gilberto González (born 1970), triathlete
- Manny Gonzalez (born 1979), umpire in Major League Baseball (MLB)
- Rodolfo González (born 1986), racing driver
- Scarlet Gruber (born 1989), actress and dancer
- Pedro Gual (1783–1862), lawyer, politician, journalist and diplomat
- Heissler Guillent (born 1986), professional basketball player
- Luis Guillorme (born 1994), professional baseball player
- Antonio Guzmán Blanco (1829–1899), military leader, statesman, diplomat and politician
- Reynaldo Hahn (1874–1947), composer, conductor, music critic, and singer.
- Veronica Hardy (born 1995), mixed martial artist.
- Carlos Morocho Hernández (1940–2016), world champion professional boxer.
- Dhison Hernández (born 1984), rower.
- Astrid Carolina Herrera (born 1963), actress and beauty queen who won Miss Venezuela World 1984, Miss World 1984.
- Francisco Herrera Luque (1927–1991), writer, psychiatrist and diplomat.
- Enrique Maggiolo (born 1974), football manager.
- Alexis Márquez (born 1989), swimmer.
- Iván Márquez (born 1981), professional and olympic volleyball player.
- Bianca Matte (born 1990), beauty queen and holder of the titles of Miss Roraima 2013 and Miss Brazilian Tourism 2014.
- Leisha Medina (born 1986), voice actress.
- Wolfgang Mejías (born 1983), épée fencer.
- Maickel Melamed (born 1975), long-distance runner, motivational speaker, financing coach, teacher in philosophy and physiotherapist.
- Henry Meléndez (born 1984), football manager.
- Carlos Méndez (born 1974), Major League Baseball first baseman/designated hitter and right-handed batter.
- Diliana Méndez (born 1982), sport shooter.
- Dayana Mendoza (born 1986), actress, model, film producer and director.
- Lorenzo Mendoza (born 1965), billionaire businessman, and CEO of Empresas Polar.
- Robinson Merchán (born 1964), professional road racing cyclist.
- Yucef Merhi (born 1977), artist, poet and computer programmer based in New York.
- Alfonso Mestre (born 2001), swimmer.
- Freddy Mezones (born 1987), sprinter specialising in the 400 metres.
- Francisco de Miranda (1750–1816), military leader and revolutionary.
- Ricardo Monasterio (born 1978), swimmer.
- Gabriela Montero (born 1970), pianist.
- Carlos Monteverde (1919–2000), sports shooter.
- Mariano Montilla (1782–1851), major general of the Army of Venezuela in the Venezuelan War of Independence.
- Nelson Mora (born 1976), butterfly swimmer.
- Omar Morales (born 1985), mixed martial artist.
- Carlos Morocho Hernández (1940–2016), world champion professional boxer.
- Garbiñe Muguruza (born 1989), professional tennis player, two-time Grand Slam champion.
- Aldo Nannini (1951–1977), professional motorcycle racer.
- Daniela Navarro (born 1983), actress and model.
- Nancy Navarro (born 1965), politician and the first Latina county council member in Montgomery County, Maryland.
- Aquiles Nazoa (1920–1976), writer, journalist, poet and humorist.
- Vicente Nebrada (1920–2002), choreographer and dancer.
- Alexander Nelcha (born 1968), basketball player.
- Luis Noguera (born 1973), taekwondo practitioner.
- Ramón Nomar (born 1974), pornographic actor.
- Erik Noya Cardona (born 1994), sport climber.
- Ana Nuño (born 1957), poet and writer.
- Riccardo Paciocco (born 1961), footballer
- Isabella Páez (born 1995), swimmer.
- Luis Arturo Paiva (born 1987), paralympic athlete.
- Bárbara Palacios Teyde (born 1963), TV host, writer, Christian preacher and beauty queen.
- Antonio José Pardo Andretta (born 1970), alpine skier.
- Isaac José Pardo (1905–2000), intellectual of German-Jewish extraction.
- Rene Paredes (born 1985), football placekicker.
- Andrea Pavani (born 1954), curler.
- Fernando Paz Castillo (1893–1981), poet, literary critic, diplomat, and educator.
- Robeilys Peinado (born 1997), athlete whose specialty is pole vaulting.
- Maylu Pena (born 1998), ballet dancer and ballet coach.
- Johan Pérez (born 1983), professional boxer.
- Luisana Pérez (born 1976), table tennis player.
- Juan Pablo Pérez Alfonzo (1903–1979), diplomat, politician and lawyer.
- Juan Antonio Pérez Bonalde (1846-1892), translator and poet.
- John Petrizzelli Font (born 1956), film director.
- Bernardo Piñango (born 1960), professional boxer.
- Félix Piñero (born 1945), fencer.
- Kervin Piñerua (1991–2016), volleyball player.
- Juan Bautista Plaza (1898–1965), classical composer.
- Lele Pons (born 1996), YouTuber, actress and singer.
- Enzo Potolicchio (born 1968), racing driver and businessman.
- Tina Ramirez (1929–2022), dancer and educator.
- Luis Razetti (1862–1932), surgeon and medicine.
- Armando Reverón (1889–1954), painter and sculptor, precursor of Arte Povera and considered.
- Wuileixis Rivas (born 1990), Greco-Roman wrestler.
- Marcel Roche (1920–2003), physician, scientist and scientific leader.
- Andres Rodriguez (1984–2016), businessman and an international show jumping competitor.
- Francisco Rodríguez (born 1982), professional baseball pitcher.
- Simón Rodríguez (1769–1854), philosopher and educator.
- Zhandra Rodríguez (born 1947), ballet dancer and choreographer
- Aldemaro Romero Jr. (born 1951), scientist, communicator, and public intellectual.
- Andy Rojas (born 1977), volleyball player.
- Arístides Rojas (born 1970), striker.
- Eloy Rojas (born 1967), professional boxer in the Featherweight division.
- Yulimar Rojas (born 1995), athlete who holds the world record for women's triple jump.
- Luis Rojas Martinez (born 1990), swimmer.
- Sheryl Rubio (born 1992), actress, singer, model, dancer, songwriter and fashion designer.
- Omar Rudberg (born 1998), singer and actor.
- Leonel Wilfredo Ruiz (born 1975), judoka.
- Miguel Ruiz (born 1990), professional basketball player.
- Yamil Saba (born 1975), windsurfer.
- Alfredo Sadel (1930–1989), singer and actor.
- Irene Sáez (born 1961) politician and beauty queen who was crowned Miss Universe 1981.
- Freddy Salazar (born 1949), fencer.
- Mayly Sánchez (born 1972), astrophysicist.
- Ingrid Sander (born 1937), fencer.
- Marcos Santana (born 1965), entrepreneur, producer and media creative, former president of NBCUniversal Telemundo Internacional.
- Carlos Santander (born 1975), swimmer.
- Nery Santos Gómez (born 1967), author.
- Daniel Sasso (born 1982), football manager.
- Maritza Sayalero (born 1961), designer, model, businesswoman and beauty queen.
- Luis Schiavo (born 1981), racing driver.
- Sabrina Seara (born 1985), telenovela actress.
- Eldric Sella (born 1997), boxer.
- Arlene Semeco (born 1984), freestyle swimmer.
- Giancarlo Serenelli (born 1981), racing driver.
- Garly Sojo (born 1999), basketball player.
- Ambrosio Solorzano (born 1937), weightlifter.
- Nelson Solórzano (born 1959), basketball player.
- Juan Soto (born 1977), football referee.
- Yadira Soturno (born 1970), paralympic athlete.
- Andrea Stock (born 1980), curler.
- Ogleidis Suárez (born 1987), professional boxer.
- Tui T. Sutherland (born 1978), children's book author.
- Lilian Tintori (born 1978), activist, athlete, and television and radio host.
- Daniele Tirabassi (born 1988), swimmer.
- Carlos J. Tirado Yepes (born 1964), artist, painter and sculptor.
- Fermín Toro (1806–1865), humanist, politician, diplomat and author.
- Juan Vicente Torrealba (1917–2019), harpist and composer of popular music.
- Gleyber Torres (born 1996), professional baseball shortstop and second baseman.
- Óscar Torres (born 1976), basketball player.
- Paul Torres (born 1983), professional racing cyclist.
- César Tovar (1940–1994), professional baseball player.
- Martín Tovar y Tovar (1827–1902), painter, best known for his portraits and historical scenes.