Branislav Nušić (1864–1938), Serbian novelist, playwright, comediographer, story writer, essayist, founder of modern Rhetoric in Serbia; lived in Novi Sad
Boško Petrović (1915–2001), Serbian novelist and poet, secretary and president of Matica Srpska; studied and lived in Novi Sad
Danilo Kiš (1935–1989), possibly the best-known ex-Yugoslavian writer alongside the Nobel laureate Ivo Andrić; lived in Novi Sad
Damjan Kaulić (1760–1810) Serbian publisher, bookseller and printer; only bookseller in Novi Sad until 1790; born in Sremski Karlovci and lived in Novi Sad.
Đura Jakšić (1831–1878), Serb poet, painter, narrator, playwright, bohemian, and patriot; born in Srpska Crnja and lived in Novi Sad
Jovan Hadžić (1799–1869; pseudonym Miloš Svetić), one of the founders of Matica srpska and its first president; poet, literary historian, interpreter, lawyer; born in Sombor and lived in Novi Sad
Jovan Jovanović Zmaj (1833–1904), one of the best-known Serb poets; born in Novi Sad
Jovan Pačić (1771–1849), poet, painter and officer; born in Baja and lived in Novi Sad
Mira Alečković (1924–2008), Serbian and Yugoslav poet; born in Novi Sad
Pavel Jozef Šafárik (1795–1861), Slovak philologist, poet; one of the first scientific Slavists; literary historian, historian and ethnographer; lived in Novi Sad
Pero Zubac (born 1945), Serbian and Yugoslav author, poet, screenwriter, academic, and journalist; born in Nevesinje in Bosnia and Herzegovina and resides in Novi Sad
Vasa Stajić (1878–1947), writer and professor; born in village Mokrin near Kikinda and lived in Novi Sad
Vasko Popa (1922–1991), Yugoslav poet of Romanian descent; lived in Novi Sad
Vuk Stefanović Karadžić (1787–1864), Serb linguist and major reformer of the Serbian language; spent 1809/1810 winter in Novi Sad
Petar Meseldžija (born 1965), fantasy and comic book artist and illustrator
Sibin Slavković (born 1953), comic book artist, illustrator and editor; created and worked on Tarzan, Il Grande Blek, Tex; born in Žunjevići and resides in Novi Sad since 1983
Emanuilo Janković (1758–1792), Serbian writer, dramatists, philosopher, translator, editor and scientist; born and raised in Novi Sad
Jovan Grčić Milenko (1846–1875) Serbian poet, writer, physician; born in Čerević lived and studied in Novi Sad
Jovan Hristić (1933–2002), Serbian poet, playwright, essayist, literary and theater critic, translator, editor; died in Sremska Kamenica in Novi Sad
Milan Savić (1845–1930), Serbian physician writer, historian, philosopher, medical doctor, geographer, literary critic, translator, president of Matica srpska; lived and studied in Novi Sad
Mladen Dražetin (1951–2015), doctor of social sciences, intellectual, economist, theatrical creator, poet, writer and philosopher. He was born and died in Novi Sad.
Slobodan Jovanović (1869–1958) Serbian and Yugoslav writer, historian, lawyer, philosopher, literary critic, diplomat, and politician; born in Novi Sad
Ivan Moscovich (1926–2023), Yugoslav-Hungarian inventor of Jewish descent, designer and commercial developer of puzzles, games, toys, and educational aids; born in Novi Sad
Đorđe Balašević (1953–2021), prominent Serbian songwriter and singer; born in Novi Sad
Isidor Bajić (1878–1915), composer; born in Kula, lived in Novi Sad
Janika Balaž (1925–1988), musician; lived in Novi Sad
Josif Runjanin (1821–1878), Serb composer and lieutenant-colonel in the Austro-Hungarian Army; born in Vinkovci in Srem (then part of Austrian Empire); died in Novi Sad
Mihajlo Obrenov (born 1982; pseudonym MiKKa), musician and composer; founder of Crime:Scene records; from Novi Sad
Milenko Paunović (1889–1924), Serbian composer and writer; author of the first Serbian musical drama; born in the village of Újszentiván in Hungary and lived in Novi Sad
Mitar Subotić (1961–1999), known as Suba and Rex Illusivi; eclectic musician and producer, electronic music pioneer in SFR Yugoslavia; born and raised in Novi Sad
Adolf Hempt (1874–1943), biologist; founder of the Pasteur Institute in Novi Sad; born in Novi Sad
Dušan Kanazir (1921–2009), Serbian molecular biologist, president of Serbian Academy of Sciences and Arts; lived and studied in Novi Sad
Miloš Marić (1885–1944), histologist; brother of Mileva Marić; head of the department of histology at the Saratov State University in Russia; researched in the field of mitosis and amitosis, which laid the foundation for cloning; born in Ruma and lived in Novi Sad
Albert Einstein (1879-1955), theoretical physicist of profound genius; widely regarded as the greatest scientist of the 20th century; lived in Novi Sad 1905-1907 (in Kisačka Street 20) with his wife, Mileva Marić
Platon Atanacković (1788–1867), Bishop of Eparchy of Bačka (1851-1867) and president of president of Matica srpska; born in Sombor, lived and died in Novi Sad
Stefan Stanković (1788–1841), Bishop of Eparchy of Buda (1829-1834), Bishop of Eparchy of Bačka (1834-1837) and Metropolitan of Sremski Karlovci (1836-1841); born in Sremski Karlovci and lived in Novi Sad
Visarion Pavlović (1670–1756), Bishop of Eparchy of Bačka (1731–1756)
Sava Tekelija (1761–1842), first Serbian doctor of law; founder of Tekelijanum; president of Matica srpska; philanthropist, noble and merchant; born in Arad in Romania
Savka Subotić (1834–1918), Serbian political activist, philanthropist and one of the first leading feminists in Vojvodina
Jovo Stanojević (born 1977), professional basketball player; born in Sombor and resides in Novi Sad
Milan Gurović (born 1975), professional basketball player with an illustrious career on the Serbia-Montenegro national team and club career stops all over Europe; born and grew up in Novi Sad
Nikola Milutinov (born 1994), professional basketball player for the Olympiacos; born and grew up in Novi Sad