Melvin Seals began playing piano at age eight and began his musical adventure playing gospel music for his local church. Over the next years he joined a few different bands in San Francisco and became good at playing other keyboards, particularly the electric organ, which he would play for the majority of his musical career. He went on to record and perform with artists such as Charlie Daniels, Elvin Bishop and Chuck Berry.[2]
In 1980 Melvin Seals joined the Jerry Garcia Band and remained a member until Jerry Garcia's death in 1995.[3] He had the third-longest tenure in the band next to Garcia and bassist John Kahn, who had been members for the band's entire history. After Garcia and Kahn's deaths in 1995 and 1996 respectively, Seals formed JGB which he performs with to this day. JGB aims to continue the Jerry Garcia Band’s legacy beyond the loss of some of its key members.[4]
Other projects Seals has been involved in include The Mix with guitarist John Kadlecik and bassist Kevin Rosen[5] and Steve Kimock's Crazy Engine with Steve Kimock. The original idea for the project was to perform original material.[6]
In 2005 Seals released his first solo CD entitled Melting Pot.[7]
Seals played two concerts with Phil Lesh & Friends at the Capitol Theatre in Port Chester, New York on May 28 and 29, 2016. This marked Seals' first collaboration with Phil Lesh & Friends. Seals had previously only played with Lesh at two Jerry Garcia Band concerts in the 1980s when Lesh sat in for their regular bassist John Kahn.[8]
In 2017 Seals toured with Oteil Burbridge on his Oteil & Friends tour, which extended into early 2018.[9]