Moricin

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Moricin
Moricin
	Solution structure of antibacterial peptide (moricin)
Identifiers
Symbol	Moricin
Pfam	PF06451
InterPro	IPR009456
SCOP2	1kv4 / SCOPe / SUPFAM
OPM superfamily	151
OPM protein	1kv4
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Moricin is a highly basic antibacterial peptide that was isolated from the silkworm Bombyx mori.^[1] It consists of a long alpha-helix with 8 turns from a 42 amino acid sequence over almost the entire protein.^[1] The amphipathic N-terminal segment of the alpha- helix is mainly responsible for the increase in permeability of the bacterial membrane which kills the bacteria.^[1] Moricin functions as an antibacterial peptide against Gram-positive and Gram-negative bacteria, with its main activity being towards Gram-positive bacteria.^[1]

References

^ ^a ^b ^c ^d ^e Hemmi H, Ishibashi J, Hara S, Yamakawa M (May 2002). "Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori". FEBS Letters. 518 (1–3): 33–8. doi:10.1016/S0014-5793(02)02637-6. PMID 11997013. S2CID 23886673.

External links

This article incorporates text from the public domain Pfam and InterPro: IPR009456

[Hemmi_2002-1] Hemmi H, Ishibashi J, Hara S, Yamakawa M (May 2002). "Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori". FEBS Letters. 518 (1–3): 33–8. doi:10.1016/S0014-5793(02)02637-6. PMID 11997013. S2CID 23886673.

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