Quinoline-4-carboxylate 2-oxidoreductase

In enzymology, a quinoline-4-carboxylate 2-oxidoreductase (EC 1.3.99.19) is an enzyme that catalyzes the chemical reaction

quinoline-4-carboxylate + acceptor + H₂O ${\displaystyle \rightleftharpoons }$ 2-oxo-1,2-dihydroquinoline-4-carboxylate + reduced acceptor

The 3 substrates of this enzyme are quinoline-4-carboxylate, acceptor, and H₂O, whereas its two products are 2-oxo-1,2-dihydroquinoline-4-carboxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating). Other names in common use include quinaldic acid 4-oxidoreductase, and quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating).

• Bauer G, Lingens F (1992). "Microbial metabolism of quinoline and related compounds. XV Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme". Biol. Chem. Hoppe-Seyler. 373 (8): 699–705. doi:10.1515/bchm3.1992.373.2.699. PMID 1418685.