Setzer is a German and Jewish occupational surname. In Middle High German setzen meant to set prices and referred to a market inspector or a tax official. In Yiddish setser referred to a typesetter.[1] Notable people with the surname include:
- Arlene Setzer, American politician
- Brian Setzer (born 1959), American guitarist and songwriter
- Dennis Setzer, American race car driver
- Matthew Setzer, American musician, composer, and music technologist
- Mitchell S. Setzer, American politician
- Franz Xaver Setzer, actually Franz Anton Adolf (born August 6, 1886, in Vienna, † January 10, 1939 ibid) was an Austrian photographer.