c. 27,000–12,000 years ago – Humans cross the Beringia land bridge into North and then South America. Dates of earliest migration to the Americas is highly debated.
c. 15,500 year old arrowhead; oldest verified arrowhead in the Americas, found in Texas.[1]
c. 10,200 BCE – Cooper Bison skull is painted with a red zigzag in present-day Oklahoma, becoming the oldest known painted object in North America.
c. 9500 BC – Cordilleran and Laurentide Ice Sheets retreat enough to open a habitable ice-free corridor through the northern half of the continent (North America) along the eastern flank of the Rocky Mountains.
c. 1450: Norse colony in Greenland dies out[citation needed].
1473 – João Vaz Corte-Real perhaps reaches Newfoundland; writes about the "Land of Cod fish" in his journal.
1479 - Treaty of Toledo ends the War of the Castilian Succession. Portugal won the exclusive right of navigating, conquering and trading in all the Atlantic Ocean south of the Canary Islands. Forcing Spain to sail west to India.
before 1492 – Population estimates in the New World before European contact may be as high as 112 million people.
1562 – Jean Ribault, leaves France with 150 colonists for the New World, establishing Charlesfort on Parris Island in South Carolina, which was abandoned several years later.
1585 – Sir Walter Raleigh founds Roanoke Colony, the first English settlement in the New World, though he never set foot in it.
1587 – Virginia Dare was born on Roanoke making her the first known English child born in the New World. The first Asians to set foot on what would be the United States occurred when Filipino sailors arrived in Spanish ships at Morro Bay, California; see Landing of the first Filipinos.
1588 – First battle of the English against the Spanish Armada begins, leading to their defeat and the lessening of Spain's influence in the New World and the rise of English influence in the Americas.
1640 – Virginia courts sentence John Punch a black indentured servant to life of servitude for running away from an abusive plantation owner Hugh Gwyn.
1662 – The Virginia Colony passed a law incorporating the principal of partus sequitur ventrem, ruling that children of enslaved mothers would be born into slavery, regardless of their father's race or status
c. 1690 – Spanish authorities, concerned that France posed a competitive threat, constructed several missions in East Texas; see Spanish Missions in Texas.
1690 – The first newspaper issue in the English colonies is published in Boston, the Public Occurrences.
1698 – The Parliament of England's Trade with Africa Act 1697 comes into effect, ending the Royal African Company's monopoly on English trade with Africa, including the Atlantic slave trade. The act, which was passed in part due to heavy pressure from merchants in England's American colonies, results in the number of Africans transported to the American colonies being increased from 5,000 to 45,000 per annum.
1699 – Capital of Virginia moved from Jamestown to Williamsburg; Jamestown is slowly abandoned. The Wool Act forbade the export of wool from the American colonies. Free blacks ordered to leave the Colony of Virginia.
1703 – Kaskaskia, Illinois established as a small mission station for the French.
1704 – The first regular newspaper publishes its initial edition in Boston, the News-Letter and was begun by John Campbell. The Province of Carolina allows the arming of the enslaved population during time of war.
1723 – The House of Burgesses passes an act to deal with slave rebellions. The French establish Fort Orleans along the Missouri River near Brunswick, Missouri.
1739-40 – George Whitefield begins his travels throughout the colonies. His message of everyday Christians having a personal connection with God resonates and begins the First Great Awakening.
^Birgitta Wallace, "The Norse in Newfoundland: L'Anse aux Meadows and Vinland." Newfoundland and Labrador Studies 19.1 (2005). onlineArchived 2014-05-19 at the Wayback Machine