The timeline of schizophrenia is a list of significant events in the creation, definition, development and continued redefinition of the diagnostic category "schizophrenia", as was originally created by the doctors of Burgholzli, the hospital clinic of the University of Zurich, during an approximately eleven year period beginning in the early 20th century.
2022: The pathogenesis of schizophrenia is unknown.
[1]
2021: The etiology of schizophrenia is unknown.[2]
2019: ICD 11th revision:The World Health Organisation ICD classification: primary psychotic disorder 6A20 Schizophrenia. For schizophrenia to be diagnosed depends on the existence for most of a 1 month duration 2 of (a) - (g) of which one of the two must be (a) - (d): Persistent delusions (a), and, or, hallucinations (b), disorganized thinking (c), experiences of influence, passivity or control (d), Negative symptoms such as affective flattening, alogia or paucity of speech, avolition, asociality and anhedonia (e), grossly disorganized behaviour that impedes goal-directed activity (f), psychomotor disturbances (g)[3][4]
2014: the Mandarin name for schizophrenia in Taiwan is changed to a word with a new meaning: “disorder with dysfunction of thought and perception” [5]
2013: DSM-5 is published. There are no tests for the purpose of diagnosis using a laboratory or by psychometric methods. Neurological imaging, pathology, and physiology research indicates the presence of abnormalities within the brain, but "none are diagnostic".[6] Schizophrenia has the Diagnostic Criteria codes: 295.90 (F20.9), and is within the group: Schizophrenia Spectrum and other psychotic disorders [7]
2012: The Korean term for schizophrenia (jungshinbunyeolbyung / jeongshin-bunyeol-byung: mind-split disorder) is changed to attunement disorder by the Korean Neuropsychiatric Association. The concept of the replacement word was inspired by the text of a South Korean monk written during 1579.[8][9]
2002: In Japan, the translation of the word schizophrenia in discontinued, replaced by Japanese words which mean "integration disorder" or ‘disintegration disorder’ [10][11][12][13]
2001: the term for schizophrenia in Hong Kong (jing-shen-fen-lie: 'mental split-mind disorder' / splitting of the mind) is changed to si-jue-shi-tiao.[14][9]
1997: an explanation for schizophrenia by neural diathesis-stress is made by Walker & Diforio via "a substantive literature on the behavioral effects of psychosocial stressors" and recent studies on "hypothalamic-pituitary-adrenal axis" cortisol activation [15][16]
1994: DSM-IV is published. Schizophrenia is encoded as 295, with the types: Catatonic, Disorganised, Paranoid, Residual, Schizophreniform, Undifferentiated [17][18]
1990: ICD 10th revision: encodes "(F20-F29)" with the descriptions: "Schizophrenia, schizotypal and delusional disorders" [19][20] The diagnostic concept is divided: Catatonic, Cenesthopathic, Hebephrenic, Paranoid, Residual, Schizophreniform, Simple, Undifferentiated, unspecified.[21]
1982: Irwin Feinberg proposes the hypothesis that a cause of schizophrenia is correlation to reduction in synaptic density within the cortex of the brain of adolescent aged individuals.[22][23][24]
1980: DSM-III is published. Diagnosis of schizophrenia depends on the existence of one of (1) - (6) for at least six months: (1): bizarre delusions (2): somatic, grandiose, religious, nihilistic, or other delusions without persecutery or jealous content (3): delusions with persecutory or jealous content if accompanied
by hallucinations of any type (4): auditory hallucinations in which either a voice keeps up a running
commentary on the individual's behavior or thoughts, or two or more
voices converse with each other (5): auditory hallucinations on several occasions with content of
more than one or two words (6): incoherence, marked loosening of associations, markedly illogical
thinking, or marked poverty of content of speech if associated with at
least one of the following: (a) blunted, flat, or inappropriate affect (b) delusions or hallucinations (c) catatonic or other grossly disorganized behavior. Encoded as 295 with the types: Disorganized, Catatonic, Paranoid, Undifferentiated, Residual.[25]
1968: DSM-II is published. Schizophrenia is within the group: Psychoses not attributed to physical conditions previously listed. The diagnostic code is 295. The concept is divided into the types: acute schizophrenic episode, catatonic, childhood, chronic undifferentiated, hebephrenic, latent, other (and unspecified) types, paranoid, residual, schizo-affective, simple.[32]
1966: Jacques Van Rossum proposes that a more than normally active or more stimulated anatomical receptors for the cerebrally neurotransmitting biochemical catecholaminedopamine could be an etiology. Catecholamines are synthesized in the adrenal medulla. [33][34][35][36]
1965: ICD 8th revision: "(290-299) Psychoses" of which the codes "295.0 - .9" are for "Schizophrenia" [37][20]
1950: Monograph Series on Schizophrenia No. 1 Dementia Praecox or the Group of Schizophrenias, an English language translation by J. Zinkin of Dr Bleuler's 1911 work is published [40]
1948: International Lists of Diseases and Causes of Death 6th revision: Dementia (309): Dementia praecox (schizophrenia) (300.7) / Schizophrenia, schizophrenic (insanity) (psychosis) (reaction) 300.7 [41]
1945: about 40,000 psychiatric patients of 283,000 patients with various diagnoses during 1939 in Germany aren't dead [42]
senior physician at Friedmatt, the Department of Psychiatry of the University of Basel and battalion physician of the Swiss army Dr Manfred Bleuler finds, from a "eugenic standpoint", sterilisation is necessary from the results of a hereditary study of "316 hospitalized schiophrenics and their 11410 relatives" [43][44][45]
1940 JANUARY: 1st group of psychiatric patients killed by carbon monoxide gas in Germany [42][46]
1939 SEPTEMBER 23: Dr Freud dies by euthanasia effected by an overdose of morphine as a consequence of the pathological effects of tobacco with the psychoactive nicotine (an addiction) in addition to or without cocaine, which were precipitative of oral cancer, diagnosed during 1923.[47][48][49][50][51][52]
1939 SEPTEMBER after 1: organization of the deaths of patients with schizophrenia directly caused by the German government.[42]
1939: FRS are included in a monograph by Schneider [55] Schneider's idea of Second Rank Symptoms include "Wahneinfall, thought inhibition (slowing or poverty of thought), flight of ideas, incoherence or dilapidation (Zerfahrenheit), compulsion".[56] The word Zerfahrenheit was created by Dr Kraepelin as the sole sign necessary for recognition of all possible forms of dementia praecox.[57]
1938 OCTOBER 3–7: ILCD 5th revision (in Europe and after the United States): Mental disorders and deficiency: "84b", defined as: "Schizophrenia (dementia praecox)" [58][20][59]
the publically known correspondance of Professor Bleuler and Dr Freud concludes with 26 letters written by Dr Freud, 53 by Professor Bleuler[69]
Schizophrenia in Japan commences to exist by the transferal of the concept by the approval of a translation of the term by a committee within the Japanese Society for Psychiatry and Neurology [13]
1934: Patients with a diagnosis of schizophrenia, which is approximately 26% of the total in Germany, are made unable to produce children via sterilisation [70]
1933 JULY 14: the German government make a law that people diagnosed with "Schizophrenia" can be sterilised.[71][42]
1920: Bertillon Committee for the International Statistical Institute (ISI 3rd revision) list: 84(1) Idiocy, Imbecility" [83][20][84]
1913:
Dementia praecox is accepted by "most British psychiatrists"[85]
Dr Kraepelin provides his most detailed description of schizophrenia[86]
1912: The government ofSwitzerland is the first country outside of the United States of America to produce a eugenics law: it becomes illegal for those diagnosed as mentally ill to marry[87][88]
1911:
Dr Bleuler's German language work: Dementia Praecox oder Gruppe der Schizophrenien is published in Leipzig & Vienna.[89][90][nb 2] Schizophrenia is a group of diseases not a sole disease. The groupings (paranoid, hebrephrenic, simple, catatonic) are entities constructed for nosology purposes not as descriptions of nature[91]
Association-splitting is a primary symptom, the secondary symptoms of sz happen because of "loosening of the associations".[92][93][94] Disturbance of associations is the "main primary symptom"[95][96] "Schizophrenic splitting" per se is "only" an "exaggerated" form of existing healthy "physiological processess" (sic).[97][98]
For treatment Dr Bleuler considers the best option available is occupation by work, even if the patient is within the acute stage, if not this, then sport, if neither are possible then preoccupation with games. Work provides the patient the opportunity to escape from an autistic existence.[99]
Dr Bleuler expresses his "hope" that sterilisation will be used in certain circumstances with regards to those diagnosed with schizophrenia "for eugenic reasons".[115]
Dr Freud's hypothesis that schizophrenia is an "inability to maintain libidinal cathexis of objects"[116]
Dr Ballet describes the nosology psychose hallucinatoire chronique[117][118]
1910: ILCD 2: Bertillon Committee for the International Statistical Institute: 67 General paralysis of the insane 68 Other forms of mental alienation 74 (A.B.C.D.) Other diseases of the nervous system 74A Idiocy, imbecility [119][20][120]
1909 MARCH 7: work at the clinic of Zurich by the direction of Dr Jung under he direction of Dr Bleuler: experiments on "word-association", is concluded by Dr Jung's resignation. The doctors who did the experiments were Dr Bleuler (clinic director), Dr Jung, Dr Riklin, Dr Fürst, Dr Binswanger, Dr Nunberg, Dr Wehrlin[121][122]
1908 APRIL 24: the term "schizophrenie" is first used at a Deutscher Verein für Psychiatrie (German Association for Psychiatry) conference in Berlin by Dr Bleuler, in a lecture entitled 'Prognosis of Dementia Praecox (Group of Schizophrenias)'. Dr Bleuler's concept is from an approximately eight year study of 647 patients [123][124][125][126][127][nb 3] The conference was the first time the Association had convened to discuss specifically dementia praecox. Maximilian Jahrmärker spoke on the ease of the diagnosing and differentiating from other psychoses of d. praecox. [141]
1907:
Indiana (in the United States of America) is the first place in the world to make a eugenics-law for the sterilisation of "idiots" and "imbeciles" [88][142]
Dr Carl Jung's work on the psychology of Dementia Praecox is published. [143] The work contains no direct reference to schizophrenia. [144] Dr Jung refers to "dissociation (Binet, Janet)" as a "weakness of consciousness due to the splitting-off of one or a series of ideas". Dr Jung discusses Otto Gross's "synchronous series" as consciousness if affected by disease in the lexicon of the "French School" which is that "associations" are "split-off", and that a split-off series of ideas occur in hysteria [145] in situations of hypnotism and with the somnambulists. [146][147][148] Dr Jung explicitly associates a "split off series of ideas" with "Freud and Gross". [149] Dr Jung in discussion of organisms sans brain, and, catatonia, in relation to automatism (the "reflex machine") propounds the notion that the reality of the catatonic state is of a complex in the mind split off ("unassailable") from any external psychological stimuli [150] In discussion of Paranoid Dementia, with reference specifically to "hysterics with dissociation of consciousness", in a first state of one consciousness, the existence of a second subsequent state of consciousness (in a temporal sequence) will not occur in the hysterics consciousness normally, and instead, the "force" of the second state of consciousness is expressed as hallucination or "other automatisms", as a split-off complex disturbing another complex. The disturbance is compared (with reference to Flournoy) as the disturance of an invisible planet in orbit to a visible planet. Split off thoughts coalesce ("crowd themselves") into consciousness forming hallucination. [151]
1904:
Bleuler begins an approximately 33 year exchange of mailed (posted) letters with Dr Freud [152]
Jung & Riklin publish: "Experimental investigations about associations of healthy people" [153]
1894: Dr Freud is inhaling ignited tobacco smoke containing the psychoactive nicotine from about 20 cigars every day [165][166]
1893: Dr Josef Breuer of Vienna and Dr Freud explain the existence of the phenomenon of "splitting of consciousness" as "present to a rudimentary degree in all forms of hysteria".[167][168]
1892: Freud begins a method of "psychical analysis" or "concentration technique" for analysis of psychology. Dr Freud begins his use of a technique and analysis which later is known as "free association" [169][170][171]
1888: Professor (1886; chef de clinique, Hôpital de la Salpêtrière, 1885) Gilbert Ballet thinks "inner speech unfolds a life of its own" which "occasionally" persist in consciousness to an extent which is to "border on auditory hallucination" [172]
1886: (eugenics) Auguste Forel is the first in Europe (as Director of Burgholzli hospital in Zurich) to sterilize someone because of a psychiatric diagnosis [173][88][157]
1884after APRIL 21 - before JUNE 19: Dr Freud first consumes and self administers cocaine in order to report on the history, pharmacology, effects, and possible medicinal use; published as Über Coca during July 1884.[184][185][186][187][188]
1883: Sir F Galton F.R.S publishes his use of: a word association test. Galton invents "eugenics".[189][190]
after MAY 1880and before MAY 1881: S Freud begins his predominantly life-long habit of tobacco consumption. During 31 March 1881 Dr S Freud qualifies as a doctor of medicine. Dr Freud's father was also a consumer of the same plant the smoke of which contains the psychoactive substance nicotine and a number of toxic substances.[191][192][193][166][194][195]
1880: "dementia praecox" is first used as a description by alienist Heinrich Schüle within Illenau asylum (construction completed 1842) in Baden, Germany.[196][197][198] Schuele's concept of nosology was made in harmony with an idea of degression from health in which insanity is progressive through generation by biological inheritance, named the theory of degeneration.[199]
1879: Francis Galton first mentions in publication the "essence" of a novel idea for psychological investigation: a word association experiment [200]
1797: the retrospective first supposed contended obvious example of the admission to an institution of an individual with thoughts and behaviours which indicate the existence of a schizophrenia-like disorder: the case of James Tilly Matthews.[227][228]
1602-8: Professor (University of Basel) Felix Platter determines within states of phrensie "spectra varia ex falsa imaginatione existiment". Platter determines lesion of the mind as association of mentis alienatio with mentis hallucinatio.[229]
circa 130 AD: Claudius Galenus Pergami (Greek: Κλαύδιος Γαληνός) recognizes the location of the phrenic nerve at the spinal cord 3rd mylotome with the diaphragm [238]
Terentius Afer (195 or 185 - 159 BCE) uses "deludier" a word of the ancient Latin language [239]
Παρανοίας γραφή (paranoías graphḗ) a legal action against insanity, as in Plato's text "Laws" (ΠλάτωνΝόμοι),[240][241] was a process in which someone could make complaint, usually against a father, or against anyone who is "mad or senile".[242][243][244]
428: In an ancient Greek theatre play by ΕΥΡΙΠΙΔΗΣ (Euripides) a nurse is made to speak on the subject of a problem which relates to φρένας (phrenes)[253][254][255]
^ abSartorius, Norman; Chiu, Helen; Heok, Kua Ee; Lee, Min-Soo; Ouyang, Wen-Chen; Sato, Mitsumoto; Yang, Yen Kuang; Yu, Xin (23 January 2014). "Name Change for Schizophrenia". Schizophrenia Bulletin. 40 (2): 255–258. doi:10.1093/schbul/sbt231. PMC3932100. PMID24457142. Retrieved 15 December 2023. jeongshin-bunyeol-byung... a lot of medical terms used in China are actually from Japan, including those of schizophrenia and dementia: the Chinese name of schizophrenia and dementia are exactly the same as the Japanese Kanji
^Lee, Yu Sang; Park, II Ho; Park, Seon-Cheol; Kim, Jae-Jin; Kwon, Jun Soo (April 2014). "Johyeonbyung (attunement disorder): Renaming mind splitting disorder as a way to reduce stigma of patients with schizophrenia in Korea". Asian Journal of Psychiatry. 8: 118–120. doi:10.1016/j.ajp.2014.01.008. PMID24655643. The term schizophrenia, which comes from the Greek roots "skhizein" and "phren," was translated as "Jungshinbunyeolbyung" in East Asian Countries, including Japan, Korea, and China.
^Sekar, Aswin; Bialas, Allison R.; de Rivera, Heather; Davis, Avery; Hammond, Timothy R.; Kamitaki, Nolan; Tooley, Katherine; Presumey, Jessy; Baum, Matthew; Van Doren, Vanessa; Genovese, Giulio; Rose, Samuel A.; Handsaker, Robert E.; Daly, Mark J.; Carroll, Michael C.; Stevens, Beth; McCarroll, Steven A. (11 February 2016). "Schizophrenia risk from complex variation of complement component 4". Nature. 530 (7589): 177–183. doi:10.1038/nature16549. PMC4752392. PMID26814963.
^Severance, Emily G.; Prandovszky, Emese; Yang, Shuojia; Leister, Flora; Lea, Ashley; Wu, Ching-Lien; Tamouza, Ryad; Leboyer, Marion; Dickerson, Faith; Yolken, Robert H. (21 September 2023). "Prospects and Pitfalls of Plasma Complement C4 in Schizophrenia: Building a Better Biomarker". Developmental Neuroscience: 1–12. doi:10.1159/000534185. PMID37734326. Complex brain disorders like schizophrenia may have multifactorial origins related to mis-timed heritable and environmental factors interacting during neurodevelopment. Infections, inflammation, and autoimmune diseases are over-represented in schizophrenia leading to immune system-centered hypotheses. Complement component C4 is genetically and neurobiologically associated with schizophrenia, and its dual activity peripherally and in the brain makes it an exceptional target for biomarker development.
^Spitzer M.D. Chairperson, Robert L.; Andreasen M.D. Ph.D., Nancy; (Arnstein M.D., Robert L.; Cantwell M.D., Dennis); Clayton M.D., Paula J.; Endicott Ph.D., Jean; (Frosch M.D., William A.; Gittelman Ph.D., Rachel; Goodwin M.D., Donald W.; Klein M.D., Donald F.; Kramer Sc.D, Morton; Lipowski, M.D., Z.J.); Mavroidis M.D., Michael L.; (Millon, Ph.D., Theodore; Pinsker, M.D., Henry; Saslow M.D. Ph.D., George; Sheehy M.D., Michael); Woodruff M.D., Robert; Wynne M.D., Ph.D, Lyman C.; Lipinski M.D., Joseph F.; Pope Jr. M.D., Harrison G.; Williams M.S.W., Janet B.W. (1980). Diagnostic and Statistical Manual of Mental Disorders (third Edition) DSM-III(PDF). The American Psychiatric Association. pp. 181–193. (p.184) Course. As noted previously, the diagnosis of Schizophrenia requires that continuous signs of the illness have lasted for at least six months which always includes an active phase of psychotic symptoms, and may or may not include prodromal or residual phases.
^Woods, Angela (2011). "4 Anti-Oedipus and the politics of the schizophrenic sublime". The Sublime Object of Psychiatry: Schizophrenia in Clinical and Cultural Theory, International Perspectives in Philosophy & Psychiatry. Oxford Academic. p. 145–161. doi:10.1093/med/9780199583959.003.0005.
^Gruenberg, Ernest M.; Jenkins, Richard L.; Kalinowsky, Lothar B.; Klein, Henriette; Pasamanick, Benjamin; Slenger, W.R.; Kramer, Morton; Spitzer, Robert L.; Kolb, Lawrence C.; Stainbrook, Edward (1968). Diagnostic and Statistical Manual of Mental Disorders (DSM-II)(PDF). Washington, D. C.: American Psychiatric Association.
^Vallone, Daniela; Picetti, Roberto; Borrelli, Emiliana (January 2000). "Structure and function of dopamine receptors". Neuroscience & Biobehavioral Reviews. 24 (1): 125–132. doi:10.1016/S0149-7634(99)00063-9. PMID10654668. S2CID9318532.
^Paravati, Stephen; Rosani, Alan; Warrington, Steven J. (24 October 2022). "Physiology, Catecholamines". StatPearls Publishing. PMID29939538. Retrieved 16 December 2023. Catecholamine synthesis within the adrenal medulla is controlled by the serum concentration of the amino acidtyrosine.
^WHO Expert Committee on Health Statistics Eighth Revision World Health Organization 12 July 1965
^ abcdeTorrey, E. F.; Yolken, R. H. (2010). "Psychiatric Genocide: Nazi Attempts to Eradicate Schizophrenia". Schizophrenia Bulletin. 36 (1): 26–32. doi:10.1093/schbul/sbp097. PMID19759092.
^Trimarchi, Matteo; Bertazzoni, Giacomo; Bussi, Mario (January 2019). "The disease of Sigmund Freud: oral cancer or cocaine-induced lesion?". European Archives of Oto-Rhino-Laryngology. 276 (1): 263–265. doi:10.1007/s00405-018-5173-3. PMID30328499. S2CID53085875.
^Franklin, James L. (28 October 2022). ""My dear neoplasm:" Sigmund Freud's oral cancer". hekint.org. Hektoen International. Retrieved 15 December 2023. JAMES L. FRANKLIN is a gastroenterologist and associate professor emeritus at Rush University Medical Center.
^Elkin, Evan J. "More Than a Cigar Sigmund Freud, the father of psychoanalysis, revered his cigars and defended his right to smoke above all else". cigar aficianado. No. George Burns • Winter 94/95. www.cigaraficionado.com. Retrieved 15 December 2023. Evan J. Elkin is a clinical psychologist interning at St. Vincent's Hospital in New York City and a research scientist at the New York State Psychiatric Institute. He is an avid cigar smoker. - And yet Freud had a partial understanding that his own penchant for cigars was significant for psychoanalysis...Freud even hinted that he felt his own addiction to smoking may have had this psychological origin. However, he never published his theory, and his abortive attempts at a theory of addiction may be the result of his ambivalence about examining his own addiction to smoking.
^Peters, U. (November 2006). "Hommage an Kraepelin zu seinem 150. Geburtstag - Zerfahrenheit: Kraepelins spezifisches Symptom für Schizophrenie". Fortschritte der Neurologie · Psychiatrie. 74 (11): 656–664. doi:10.1055/s-2006-944302. PMID17103366. S2CID144264882.
^Commission of Statistical Experts Fifth Revision International Institute of Statistics and the Health Organization of the League of Nations October 1938
^Ceccherini-Nelli, Alfonso; Crow, Timothy J. (March 2003). "Disintegration of the components of language as the path to a revision of Bleuler's and Schneider's concepts of schizophrenia: Linguistic disturbances compared with first-rank symptoms in acute psychosis". British Journal of Psychiatry. 182 (3): 233–240. doi:10.1192/bjp.182.3.233. PMID12611787.
^Moscarelli, Massimo (July 2020). "A major flaw in the diagnosis of schizophrenia: what happened to the Schneider's first rank symptoms". Psychological Medicine. 50 (9): 1409–1417. doi:10.1017/S0033291720001816. PMID32524921. S2CID219587791.
^Soares-Weiser, Karla; Maayan, Nicola; Davenport, Clare; Kirkham, Amanda J; Adams, Clive E (16 July 2013). Soares-Weiser, Karla (ed.). "First-rank symptoms for schizophrenia". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD010653.
^Peralta, Victor; Cuesta, Manuel J (April 2023). "Schneider's first-rank symptoms have neither diagnostic value for schizophrenia nor higher clinical validity than other delusions and hallucinations in psychotic disorders". Psychological Medicine. 53 (6): 2708–2711. doi:10.1017/S0033291720003293. PMID32943125.
^Peralta, Victor; Cuesta, Manuel J. (March 1999). "Diagnostic significance of Schneider's first-rank symptoms in schizophrenia: Comparative study between schizophrenic and non-schizophrenic psychotic disorders". British Journal of Psychiatry. 174 (3): 243–248. doi:10.1192/bjp.174.3.243. PMID10448450. S2CID1357826.
^Maetzener, Christian (June 2018). "The Freud-Bleuler Correspondence: German Edition". Journal of the American Psychoanalytic Association. 66 (3): 549–568. doi:10.1177/0003065118777453. S2CID49689741.
^Devine, Henry (8 November 1932). "The Problem of Schizophrenia". Proceeding of the Royal Society of Medecine. 26 (2): 1. doi:10.1177/003591573202600211. Retrieved 17 December 2023. Having spent some twenty-five years in almost daily contact with psychotic patients, it is only natural to wish I felt myself to be in a position to speak with assurance on the causation, pathology, and treatment of the reaction-type to which the term schizophrenia is applied.
^Bryant, P.J. (26 January 1994). "A Brief History and Review of Accelerators"(PDF). Geneva, Switzerland: CERN Organisation européenne pour la recherche nucléaire Accelerator School. p. 1. Retrieved 17 December 2023. ed. note: page 2 has an erratum, page 12 ("Livingston chart") shows the changes in scale of energies used for accelarators in disintegrations "1930" - "1980"+
^Cox, Hayley (10 October 2017). "100 years on, marking Rutherford's breakthroughs". www.mub.eps.manchester.ac.uk. University of Manchester. Retrieved 18 December 2023. Rutherford is often credited with splitting the atom during this period...Sean Freeman, Professor of Nuclear Physics at the University, explains: '"Splitting the atom" is not a particularly good description of this work.:
^E. Roesle Commission of Expert Statisticians Fourth Revision International Statistical Institute (Michel Huber), Health Organization of the League of Nations
^Lanzoni, Susan (2006). "Diagnosing with Feeling: The Clinical Assessment of Schizophrenia in Early Twentieth-Century European Psychiatry". Medicine, Emotion and Disease, 1700–1950. pp. 169–190. doi:10.1057/9780230286030_8. ISBN978-1-349-54036-5.
^McKenna, Peter J.; Oh, Tomasina M. (2005). Schizophrenic Speech: Making Sense of Bathroots and Ponds that Fall in Doorways. Cambridge University Press. p. 2. ISBN978-0-521-81075-3.
^Lucassen, Leo (August 2010). "A Brave New World: The Left, Social Engineering, and Eugenics in Twentieth-Century Europe". International Review of Social History. 55 (2): 265–296. doi:10.1017/S0020859010000209.
^ abcLuty, Jason (January 2014). "Psychiatry and the dark side: eugenics, Nazi and Soviet psychiatry". Advances in Psychiatric Treatment. 20 (1): 52–60. doi:10.1192/apt.bp.112.010330.
^Moskowitz, A.; Heim, G. (May 2011). "Eugen Bleuler's Dementia Praecox or the Group of Schizophrenias (1911): A Centenary Appreciation and Reconsideration". Schizophrenia Bulletin. 37 (3): 471–479. doi:10.1093/schbul/sbr016. PMID21505113.
^Nestor, Paul G; Levitt, James J; Ohtani, Toshiyuki; Newell, Dominick T; Shenton, Martha E; Niznikiewicz, Margaret (2022). "Loosening of Associations in Chronic Schizophrenia: Intersectionality of Verbal Learning, Negative Symptoms, and Brain Structure". Schizophrenia Bulletin Open. 3 (1). doi:10.1093/schizbullopen/sgac004. PMID35295655.
^Ceccherini-Nelli, Alfonso; Crow, Timothy J. (March 2003). "Disintegration of the components of language as the path to a revision of Bleuler's and Schneider's concepts of schizophrenia: Linguistic disturbances compared with first-rank symptoms in acute psychosis". British Journal of Psychiatry. 182 (3): 233–240. doi:10.1192/bjp.182.3.233. PMID12611787.
^Bleuler, Eugen (1911) Dementia Praecox oder Gruppe der Schizophrenien (MONOGRAPH SERIES ON SCHIZOPHRENIA NO. 1 Dementia Praecox or the Group of Schizophrenias) archive.org International Universities Press (Translated by J. Zinkin with the help of L.W. Zinkin, 1950. New York) 362: "The splitting is the prerequisite condition of most of the coinplicated phenomena of the disease. It is the splitting which gives the peculiar stamp to the entire symptomatology. However, behind this systematic splitting into definite idea-complexes, we have found a previous primary loosening of the associational structure which can lead to an irregular fragmentation of such solidly established elements as concrete ideas. The term, schizophrenia, refers to both kinds of splitting which often fuse in their effects. Schizophrenic splitting is again only another example of exaggerated physiological processess. Even the healthy person can harbor various complexes, all more or less unconnected with each other; and he may even continue to elaborate and develop them in his unconscious or in dreams."
^Stotz-Ingenlath, Gabriele (2000). "Epistemological aspects of Eugen Bleuler's conception of Schizophrenia in 1911". Medicine, Health Care and Philosophy. 3 (2): 153–159. doi:10.1023/A:1009919309015. PMID11079343. S2CID25457004. so-called pathological phenomena actually seemed to be only exaggerations of normal psychic functions. So there were only a quantitative, not a qualitative difference between schizophrenia and normal psychic processes
^Bleuler, Eugen (1911). Dementia Praecox oder Gruppe der Schizophrenien (MONOGRAPH SERIES ON SCHIZOPHRENIA NO. 1 Dementia Praecox or the Group of Schizophrenias). International Universities Press (Translated by J. Zinkin with the help of L.W. Zinkin, 1950. New York). pp. 476-8. At the present time, the only type of therapy that can seriously be considered for schizophrenia as a whole is the psychic method...At present, there is nothing we can do at the peak of an active thrust of the disease. We are forced to wait for improvement. However, in many cases, it is difficult to recognize when the end of the acute stage has been reached...The general tasks or treatment, then, consist in educating the patient in re-establishing his contact with reality, i.e., in combatting autism...Occupational therapy represents the best means of meeting our demands. It provides an opportunity for exercising the normal psychic functions, for continual active and passive contact with reality, it stimulates the patients' capacity for adaptation, and forces them to think about normal life outside the hospital. After all, in the absence of some such external means, it is impossible for anyone to maintain for any length of time psychic contact with individuals with whom one does not have any spiritual rapport. Even in acute stages, occupational therapy proves often both practical and useful. Every mental institution should have the kind of set-up that will make it possible to offer every patient some kind of work at all times... Sports may also be considered as an inferior substitute for work. However, as an addition to work, it is of considerable value when dealing with people who are well acquainted with it. Otherwise, games...
^ abMoskowitz, A.; Heim, G. (May 2011). "Eugen Bleuler's Dementia Praecox or the Group of Schizophrenias (1911): A Centenary Appreciation and Reconsideration". Schizophrenia Bulletin. 37 (3): 471–479. doi:10.1093/schbul/sbr016. PMID21505113.
^A.A. Brill (1909) In: "The physiological psychologist" Kieran McNally Looking Back: Treasures of knowledge the british psychological society 18 October 2013 "Based on experimental psychology, and on the new and invaluable psychology of Freud..."
^Bleuler, Eugen (1911). "Author's Preface" In: Monograph Series on Schizophrenia No. 1 Dementia Praecox or the Group of Schizophrenias (Dementia Praecox oder Gruppe der Schizophrenien). archive.org: International Universities Press (Translated by J. Zinkin, 1950). p. 1. Our knowledge of the disease group which Kraepelin established under the name of Dementia Praecox is too recent to warrant a complete description. The whole complex is still too fluid, incomplete, tentative.... An additional difficulty arises with regard to the chapters on psychopathology, that is the embryonic state of contemporary psychology. We do not even have the necessary terminology for the new psychological concepts.... An important aspect of the attempt to advance and enlarge the concepts of psychopathology is nothing less than the application of Freud's ideas to dementia praecox. I feel certain that every reader realizes how greatly we are indebted to this author, without my mentioning his name at each appropriate point of the discussion.
^Kieran McNally "A psychological persuasion" "The physiological psychologist" History and philosophy Looking Back: Treasures of knowledge. "Based on experimental psychology, and on the new and invaluable psychology of Freud." A.A. Brill, 1909
Under all circumstances, if the disease is diagnosed or suspected, marriage must be discouraged with the greatest emphasis...we know of no measures which will cure the disease, as such, or even bring it to a halt...it is to be hoped that sterilisation will soon be employed on a larger scale in these cases as in other patients with a pathological Anlage for eugenic reasons
^Freeman, T (1977). "On Freud's theory of schizophrenia". The International Journal of Psycho-analysis. 58 (4): 383–388. PMID340399. For many years now there has been a continued and sustained criticism of Freud's (1911) hypothesis that the basic disorder in schizophrenia consists of the patient's inability to maintain libidinal cathexis of objects.
^Haustgen, T. (September 2007). "La psychose hallucinatoire chronique doit-elle disparaître ? Une revue historique". PSN. 5 (3): 162–175. doi:10.1007/s11836-007-0041-z. S2CID142547341.
^Ferreira, M.C.; Sousa-Ferreira, T.; Almeida, N.; Santos, B. (March 2015). "Can We Still Talk About Chronic Hallucinatory Psychosis? a Case Report". European Psychiatry. 30: 1689. doi:10.1016/S0924-9338(15)31295-5. S2CID147500729. The growing influence of international nosology has led to a progressive disuse of the concept of chronic hallucinatory psychosis and patients with such clinical condition have been classified under the diagnosis of paranoid schizophrenia, according to the Anglo-Saxon current classifications.
^Manual of the International List of Causes of Death, as adapted for use in England and Wales. ased on the Decennial Revision of the International Commission Paris, 1909 London: Published by His Majesty's Stationary Office p.xviifacsimile published by archive.org 2015-02-25
^Möller, A.; Scharfetter, C.; Hell, D. (October 2002). "Development and termination of the working relationship of C. G. Jung and Eugen Bleuler, 1900-1909". History of Psychiatry. 13 (52): 445–453. doi:10.1177/0957154X0201305206. PMID12645573. S2CID39653638.
^Studies in Word-Association Experiments in the Diagnosis of Psychopathological Conditions carried out at the Psychiatric Clinic of the University of Zurich under the direction of C. G. Jung M.D., LL.D. (formerly of the University of Zurich) authorized translation by Dr. M.D. Eder. New York Moffat, Yard & Company 1919
^Lee, Yu Sang; Park, II Ho; Park, Seon-Cheol; Kim, Jae-Jin; Kwon, Jun Soo (April 2014). "Johyeonbyung (attunement disorder): Renaming mind splitting disorder as a way to reduce stigma of patients with schizophrenia in Korea". Asian Journal of Psychiatry. 8: 118–120. doi:10.1016/j.ajp.2014.01.008. PMID24655643.
^Fusar-Poli, Paolo; Politi, Pierluigi (November 2008). "Paul Eugen Bleuler and the Birth of Schizophrenia (1908)". American Journal of Psychiatry. 165 (11): 1407. doi:10.1176/appi.ajp.2008.08050714. PMID18981075.
^Crespi, Bernard J. (June 2010). "Revisiting Bleuler: relationship between autism and schizophrenia". British Journal of Psychiatry. 196 (6): 495. doi:10.1192/bjp.196.6.495. PMID20513864.
^Gina Ryder and Christie Craft medically reviewed by Matthew Boland, PhD The History of Schizophrenia Healthline Media
^Stam, J.; Vermeulen, M. (June 2013). "Eugen Bleuler (1857-1939), an early pioneer of evidence based medicine". Journal of Neurology, Neurosurgery & Psychiatry. 84 (6): 594–595. doi:10.1136/jnnp-2012-303715. PMID23236013.
^Manassa Hany; Baryiah Rehman; Yusra Azhar; Jennifer Chapman. Schizophrenia Treasure Island (FL): StatPearls Publishing; 2023 Jan
Dissociation according to the French school is a weakness of consciousness due to the splitting off of one or a series of ideas. They separate themselves from the hierarchy of the conscious ego and begin a more or less independent existence.77 The hysteria doctrine of Breuer and Freud was developed on this foundation...77 See the fundamental work of Janet : L'automatisme psychologique....If the connection between Gross's synchronous series is severed by disease, disintegration of consciousness results. Translated into the language of the French school, it means that if one or more association series are split off there results a dissociation causing weakness of consciousness. Let us not quarrel over words....As aforesaid, the displeasing part in this hypothesis is the assumption of synchronous independent association series. Normal psychology does not furnish us with any facts on this point. Where we can best observe split-off series of ideas, namely, in hysteria, we find that the opposite holds true.
If we weaken the power of consciousness by suggestion and produce thereby a split-off series of presentations, as, for example, in post-hypnotic commands, we find that this series reappears with a power inexplicable to the ego-consciousness. In the psychology of ecstatic somnambulists we have the typical breaking in of split-off ideas.84...84 See especially the magnificent script examples of Helene Smith, Flournoy: Des Indes, etc.
^Jastrow, Joseph (July 1900). "Des Indes à la Planète Mars. Etude sur un cas de somnambulisme avec glossolalie [From India to the planet Mars: A study of a case of somnambulism with glossolalia]". Psychological Review. 7 (4): 406–411. doi:10.1037/h0069534.
Freud and Gross find the important fact of the presence of split-off series of ideas. To Freud, however, belongs the credit of being the first to show in a case of paranoid dementia praecox the " principle of conversion " (repression and indirect reappearance of the complexes).
^p.96: section on "Sterotypy" in the Chapter "Dementia Praecox and Hysteria" 1907
^Bleuler, Eugen (1911) Dementia Praecox oder Gruppe der Schizophrenien (Monograph Series on Schizophrenia NO. 1 Dementia Praecox or the Group of Schizophrenias) archive.org International Universities Press (Translated by J. Zinkin with the help of L.W. Zinkin, 1950. New York) p.9: "The Definition of the Disease
at different times different psychic complexes seem to represent the personality. Integration of different complexes and strivings appears insufficient or even lacking. The psychic complexes do not combine in a conglomeration of strivings with a unified resultant as they do in a healthy person; rather, one set of complexes dominates the personality for a time, while other groups of ideas or drives are "split off" and seem either partly or completely impotent."
^ abBleuler, Manfred; Bleuler, Rudolf (November 1986). "Dementia praecox oder die Gruppe der Schizophrenien: Eugen Bleuler". British Journal of Psychiatry. 149 (5): 661–664. doi:10.1192/bjp.149.5.661. PMID3545358. S2CID5881202.
^Chamberlain, J. P. (1923). "Current Legislation: Eugenics and Limitations of Marriage". American Bar Association Journal. 9 (7): 429–430. JSTOR25711334.
^ abLaviolette, Steven R.; van der Kooy, Derek (2004). "The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour". Nature Reviews Neuroscience. 5 (1): 55–65. doi:10.1038/nrn1298. PMID14708004. S2CID12559343. Nicotine, the primary psychoactive component of tobacco smoke, produces diverse neurophysiological, motivational and behavioural effects through several brain regions and neurochemical pathways. Recent research in the fields of behavioural pharmacology, genetics and electrophysiology is providing an increasingly integrated picture of how the brain processes the motivational effects of nicotine.
^Jack S. Blocker Jr., David M. Fahey, Ian R. Tyrrell p.245 In: Alcohol and Temperance in Mode rn History: An International Encyclopedia] Bloomsbury Publishing USA, 17 Dec 2003
^Bogousslavsky, Julien; Boller, François (2013). "Jean-Martin Charcot and art". The Fine Arts, Neurology, and Neuroscience - Neuro-Historical Dimensions. Progress in Brain Research. Vol. 203. pp. 185–199. doi:10.1016/B978-0-444-62730-8.00007-4. ISBN978-0-444-62730-8. PMID24041281. the "father of neurology" in France and much beyond, was also the man who established academic psychiatry in Paris, differentiating it from clinical alienism.
^Bowden-Jones, Owen (2016). "What are psychoactive drugs, who uses them and why?". The Drug Conversation: How to Talk to Your Child about Drugs. Royal College of Psychiatrists. ISBN978-1-909726-57-4.
^Lebzeltern, G (11 November 1983). "Freud und das Kokain" [Sigmund Freud and cocaine]. Wiener klinische Wochenschrift (in German). 95 (21): 765–769. PMID6369804.
^Trimarchi, Matteo; Bertazzoni, Giacomo; Bussi, Mario (January 2019). "The disease of Sigmund Freud: oral cancer or cocaine-induced lesion?". European Archives of Oto-Rhino-Laryngology. 276 (1): 263–265. doi:10.1007/s00405-018-5173-3. PMID30328499. S2CID53085875.
^Shorter, Edward; Fink, Max (May 2018). "3 Karl Kahlbaum". The Madness of Fear: A History of Catatonia. Vol. 1. New York: Oxford Academic. doi:10.1093/med/9780190881191.003.0003.
^Hirjak, Dusan; Foucher, Jack R.; Ams, Miriam; Jeanjean, Ludovic C.; Kubera, Katharina M.; Wolf, Robert Christian; Northoff, Georg (June 2022). "The origins of catatonia – Systematic review of historical texts between 1800 and 1900". Schizophrenia Research. doi:10.1016/j.schres.2022.06.003. S2CID249628976.
^Fusar-Poli, Paolo; Salazar de Pablo, Gonzalo; Rajkumar, Ravi Philip; López-Díaz, Álvaro; Malhotra, Savita; Heckers, Stephan; Lawrie, Stephen M; Pillmann, Frank (January 2022). "Diagnosis, prognosis, and treatment of brief psychotic episodes: a review and research agenda". The Lancet Psychiatry. 9 (1): 72–83. doi:10.1016/S2215-0366(21)00121-8. hdl:10261/306651. PMID34856200. S2CID244762119.
^Coffin, Jean -Christophe (May 2004). "Conceptions de la dégénérescence dans la psychiatrie italienne du XIXème siècle". PSN. 2 (3): 46–59. doi:10.1007/BF03005222. S2CID141139989.
^Burgy, M. (20 August 2008). "The Concept of Psychosis: Historical and Phenomenological Aspects". Schizophrenia Bulletin. 34 (6): 1200–1210. doi:10.1093/schbul/sbm136. PMID18174608.
^Canstatt, Carl Friedrich (1843). Handbuch der medicinischen Klinik : die Specielle Pathologie und Therapie vom klinischen Standpunkte aus bearbeitet (in German). Vol. Erster Band (first volume) (Zweite vermehrte Auflage: Second enlarged ed.). Erlangen: F. Enke. p. 337. Retrieved 9 December 2023 – via archive.org (Royal College of Physicians of Edinburgh). §. 50. Die Frage, welchen Ausgang eine Neurose im concreten Falle nehmen werde, ist gar nicht zu beantworten ohne Hinblick auf die Grundzustände, die, an und für sich ein Anderes als die Neurose, nur unter der Form derselben in die äussere Erscheinung treten. Diess hat man aber oft genug übersehen und hat z.B. für Krise der Neurosen genommen , wras, beim Lichte betrachtet, Ausgang primären mit der Neurose ursächlich zusammenhängenden Leidens wTar. So können wir unmöglich zugeben, dass eine Neuralgia coeliaca sich durch Blutbrechen oder Meiäna, eine Psychose durch Darmausleerungen, eine Lähmung durch Nasenbluten u. dgl. m. entscheide; materielle Krisen sind nur im und vom vegetativen Systeme aus möglich; jene Entleerungen sind Aeusserungen einer sich wieder ins Gleichgewicht setzenden Plastik und können zur Heilung der Neurose beilragen, wenn sie das sie bedingende Grundleiden heben; aber sie stehen in keinem unmittelbaren Verbände mit den erkrankten Nerven, sind keine Metamorphose innerhalb der Neurose selbst. Dass uns gar oft jene Anomalieen der Vegetation verborgen bleiben, dass uns solche materielle Krisen, welche die Neurose oft mit Einem Sclilage heben, nicht selten überraschen und wir vergeblich nach ihrem inneren Zusammenhänge forschen, ändert Nichts an der Sache. Je weiter wir in der ätiologischen Kenntniss der Neurosen (und sie ist gewiss die wichtigere!) Vordringen werden, desto weniger werden wir an diesen Rälhseln zu kauen haben. Wie häufig aber Bildungskrankheilen und Degenerationen Ursache der Neurosen sind , lehrt uns das in neuerer Zeit auch in diesem Gebiete der pathologischen Aanatomie sorgfältiger forschende Scalpell. §. 51. Man hat auch von nervösen Krisen gesprochen.
^"168 Jahre Museumsgeschichte". www.bayerisches-nationalmuseum.de/en/museum/history. Bayerisches Nationalmuseum 2023. Retrieved 10 December 2023.
^"Die innere Politik 1825–1848". hdbg.eu/. Haus der Bayerischen Geschichte Museum. 2023. Retrieved 10 December 2023. Vormärz und Revolutionsangst Die Ära Ludwigs I. (1825–1848) fällt in die Zeit des „Vormärz", der langen Phase zwischen dem Wiener Kongress von 1814/15 und der Märzrevolution von 1848.
^Ahonen, Marke (March 2019). "Ancient philosophers on mental illness". History of Psychiatry. 30 (1): 3–18. doi:10.1177/0957154X18803508.
^Serafim, Andreas (6 July 2022). "Religion on the Rostrum: Euchomai Prayers in the Texts of Attic Oratory". Trends in Classics. 14 (1): 93–123. doi:10.1515/tc-2022-0004.
^Πλάτων. "Plato, The Apology of Socrates Translated by Benjamin Jowett Adapted by Miriam Carlisle, Thomas E. Jenkins, Gregory Nagy, and Soo-Young Kim". chs.harvard.edu. The Center for Hellenic Studies, Harvard University. Retrieved 14 December 2023. I have said enough in my defense against the first class of my accusers; I turn to the second class, who are headed by Meletus, that good [agathos] and patriotic man, as he calls himself. And now I will try to defend myself against them: these new accusers must also have their affidavit read...Socrates commits wrong [a-dika] deeds, and corrupts the young men, and he does not believe in the gods that the state [polis] believes in, but believes in other things having to do with daimones of his own. That is the sort of charge
^McCarthy-Jones, Simon (2012). Hearing Voices: The Histories, Causes and Meanings of Auditory Verbal Hallucinations. Cambridge University Press. pp. 19–20. ISBN978-1-107-00722-2.
^Berman, David (2014). "Socrates' Daimonion". Encyclopedia of Psychology and Religion. pp. 1676–1679. doi:10.1007/978-1-4614-6086-2_652. ISBN978-1-4614-6085-5. I have a divine sign [daimonion] from the god which… began when I was a child. It is a voice
Douglas Harper Etymology of conscience - from Latin conscientia "knowledge within oneself" probably originally (Harper) "to separate one thing from another, to distinguish," scindere "to cut, divide," skhizein "to split, rend, cleave"
^During 14 April a method for the splitting of an atom is discovered. An atom of lithium is made disintegrational by John Cockcroft and Ernest Walton using a particle accelerator (after Rutherford) designed to study nuclear reactions. The disintegrational products are transmutations. [73][74][75][76][77][78] see: 1948
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