The Argentine War of Independence was fought from 1810 to 1818 by Argentine patriotic forces under Manuel Belgrano, Juan José Castelli and José de San Martín against royalist forces loyal to the Spanish crown. On July 9, 1816, an assembly met in San Miguel de Tucumán, declared full independence with provisions for a national constitution.
- The government of Spain is defeated by French forces and the Supreme Central and Governing Junta was replaced by the Regency
- The Cortes of Cádiz convenes in Spain
- An open cabildo in Buenos Aires deposes the viceroy and creates a government junta.
- Córdoba rejects the Junta of Buenos Aires. Liniers leads a counter-revolution, which is defeated. Liniers is executed as result.
- Buenos Aires organizes military campaigns against Paraguay and the Upper Peru.
- March 10: A group of royalist scouts is captured during the action of Juncalito.
- Only the region of the Río de la Plata remains under patriotic control.
- The prince Juan raises Brazil to a kingdom and keeps the expansionist policy towards the Rio de la Plata. Their forces invade the Banda Oriental, and Artigas organizes the resistance
- The Congress of Tucumán starts working
- Trienio Liberal disband the military Great Expedition against the Rio de la Plata
- José de San Martin leaves Chile with the navy, aiming to defeat the royalists at Peru
- The United States recognizes the independence of the former Spanish colonies
- Bolívar and San Martin meet at Guayaquil
- San Martin fails to defeat the royalists in Peru, resigns from power and leaves Lima