Tomko is a surname. Notable people with the surname include:
- Al Tomko (1931–2009), Canadian professional wrestler and wrestling promoter
- Brett Tomko (born 1973), Major League Baseball pitcher with the Kansas City Royals
- Dewey Tomko (born 1946), American professional poker player
- Jozef Tomko (1924–2022), Slovak cardinal in the Roman Catholic Church
- Sara Tomko, American actress
- Travis Tomko (born 1976), aka Tomko, American professional wrestler