Vegetation (pathology)

In medicine, a vegetation is an abnormal growth^[1] named for its similarity to natural vegetation. Vegetations are often associated with endocarditis.^[2]^[3]^[4] They can be made of fibrin^[5] and platelets.^[6]

Types

Certain conditions are associated with specific vegetation patterns:

Condition	Size	Infective?
Infective endocarditis related to Staphylococcus aureus	Generally large	Yes
Rheumatic fever related to Streptococcus pyogenes	Typically small
Libman–Sacks endocarditis related to systemic lupus erythematosus	Small	No (sterile)
Nonbacterial thrombotic endocarditis (NBTE)	Small	No (sterile)

^ "Vegetation" at Dorland's Medical Dictionary
^ Miyata E, Satoh S, Inokuchi K, et al. (September 2007). "Three fatal cases of rapidly progressive infective endocarditis caused by Staphylococcus aureus: one case with huge vegetation". Circ. J. 71 (9): 1488–91. doi:10.1253/circj.71.1488. PMID 17721034.
^ Gotsman I, Meirovitz A, Meizlish N, Gotsman M, Lotan C, Gilon D (May 2007). "Clinical and echocardiographic predictors of morbidity and mortality in infective endocarditis: the significance of vegetation size". Isr. Med. Assoc. J. 9 (5): 365–9. PMID 17591374.
^ "eMedicine/Stedman Medical Dictionary Lookup!". Archived from the original on 2008-02-16.
^ "Pathology Education: Cardiovascular".
^ "eMedicine/Stedman Medical Dictionary Lookup!". Archived from the original on 2008-02-16.

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